0000000000598927
AUTHOR
Barbara Kienzle
The Calgary Depression Rating Scale for schizophrenia in a healthy control group: Psychometric properties and reference values
Abstract Background Assessment of depression in schizophrenia is of great importance as depressive signs and symptoms and suicidality are highly prevalent in patients with schizophrenic disorders. The Calgary Depression Rating Scale (CDSS) is the standard assessment instrument for that purpose due to its proven reliability and validity. However, so far no reference values derived from an adequate healthy sample have been published. Methods The present study analyzed CDSS item scores and summary scores in 154 healthy subjects (49% female, mean age 32.8 ± 11.7 years) selected from studies as controls for schizophrenic patients. Results The total CDSS score was 2.6 ± 2.7 (range 0–12), about 1/…
Differentiating moderate and severe depression using the Montgomery–Åsberg depression rating scale (MADRS)
MADRS cut-off scores for moderate and severe depression were estimated in relation to the Hamilton Depression Rating Scale (HAMD(17)) and the Clinical Global Impressions Scale (CGI).HAMD(17), MADRS, and CGI ratings from patients with major depression (DSM-IV) were analyzed (N=85). Receiver operating characteristics (ROC) curves were applied.Mean age was 51.4+/-14.5 years, 69% were female. Mean MADRS scores were 23.4+/-13.2, HAMD(17), MADRS, and CGI scores were highly correlated (r0.85; P0.0001). Best separation between moderate and severe depression according to CGI criteria was achieved with a MADRS score of 31 (sensitivity 93.5%, specificity 83.3%).Studies to validate severity gradations …