0000000000599004

AUTHOR

M. R. Gismondo

showing 2 related works from this author

Prevalence of acquired resistance mutations in a large cohort of perinatally infected HIV-1 patients

2019

Maleantiretroviral treatmentInfectious Disease TransmissiongenotypeHuman immunodeficiency virus (HIV)Drug ResistanceHIV InfectionsDrug resistancemedicine.disease_causeRetrospective StudieGenotypepol Gene Products Human Immunodeficiency ViruPrevalenceMedicineVerticalHIV InfectionViralpol Gene ProductsYoung adultGeneral MedicineInfectious DiseasesItalyMutation (genetic algorithm)FemaleHuman Immunodeficiency VirusHumanMicrobiology (medical)AdultSettore MED/17 - Malattie InfettiveAdolescentAnti-HIV AgentsYoung AdultAcquired resistanceDrug Resistance ViralHumansvertical HIV transmissionAdolescent; Adult; Anti-HIV Agents; Drug Resistance Viral; Female; HIV Infections; HIV-1; Humans; Italy; Male; Mutation; Prevalence; Retrospective Studies; Young Adult; pol Gene Products Human Immunodeficiency Virus; Infectious Disease Transmission VerticalRetrospective StudiesHIV perinatally infectionbusiness.industryAnti-HIV AgentRetrospective cohort studyVirologyInfectious Disease Transmission VerticalLarge cohortpol Gene Products Human Immunodeficiency VirusDrug resistanceMutationHIV-1Drug resistance; HIV-1; antiretroviral treatment; genotype; vertical HIV transmissionbusiness
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Co-circulation of SARS-CoV-2 Alpha and Gamma variants in Italy, February and March 2021

2022

Background Several SARS-CoV-2 variants of concern (VOC) have emerged through 2020 and 2021. There is need for tools to estimate the relative transmissibility of emerging variants of SARS-CoV-2 with respect to circulating strains. Aim We aimed to assess the prevalence of co-circulating VOC in Italy and estimate their relative transmissibility. Methods We conducted two genomic surveillance surveys on 18 February and 18 March 2021 across the whole Italian territory covering 3,243 clinical samples and developed a mathematical model that describes the dynamics of co-circulating strains. Results The Alpha variant was already dominant on 18 February in a majority of regions/autonomous provinces (…

EpidemiologySARS-CoV-2Public Health Environmental and Occupational HealthCOVID-19co-circulation; lineage; SARS-CoV-2 variant of concern; transmissibility; Humans; Italy; Models Theoretical; COVID-19; SARS-CoV-2Models TheoreticalSettore MED/42 - Igiene Generale E ApplicataSARS-CoV-2 variant of concern; co-circulation; lineage; transmissibility; Humans; Italy; Models Theoretical; COVID-19; SARS-CoV-2SARS-CoV-2 variant of concernSARS-COV-2 VARIANT OF CONCERN CO-CIRCULATION LINEAGE TRANSMISSIBILITY HUMANS ITALY MODELS THEORETICAL COVID-19 SARS-COV-2ItalyTheoreticalModelsVirologytransmissibilityHumansHumanco-circulationlineage
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