0000000000599629
AUTHOR
Alberto Zanella
showing 11 related works from this author
Additional file 2 of Mechanical ventilation parameters in critically ill COVID-19 patients: a scoping review
2021
Additional file 2. Online search strategy; Table S1; Table S2; Table S3. Description of data: additional file 2 contains the full online search strategy, Table S1 summarizing the characteristics of the included studies, Table S2 assessing the quality of the included studies and table S3 reporting the inclusion and exclusion criteria of the present review.
Mechanical ventilation parameters in critically ill COVID-19 patients: a scoping review
2021
Abstract Background The mortality of critically ill patients with COVID-19 is high, particularly among those receiving mechanical ventilation (MV). Despite the high number of patients treated worldwide, data on respiratory mechanics are currently scarce and the optimal setting of MV remains to be defined. This scoping review aims to provide an overview of available data about respiratory mechanics, gas exchange and MV settings in patients admitted to intensive care units (ICUs) for COVID-19-associated acute respiratory failure, and to identify knowledge gaps. Main text PubMed, EMBASE, and MEDLINE databases were searched from inception to October 30, 2020 for studies providing at least one v…
Characteristics and outcomes of an international cohort of 600 000 hospitalized patients with COVID-19
2023
Abstract Background We describe demographic features, treatments and clinical outcomes in the International Severe Acute Respiratory and emerging Infection Consortium (ISARIC) COVID-19 cohort, one of the world's largest international, standardized data sets concerning hospitalized patients. Methods The data set analysed includes COVID-19 patients hospitalized between January 2020 and January 2022 in 52 countries. We investigated how symptoms on admission, co-morbidities, risk factors and treatments varied by age, sex and other characteristics. We used Cox regression models to investigate associations between demographics, symptoms, co-morbidities and other factors with risk of death, admiss…
The value of open-source clinical science in pandemic response
2021
International audience
Machine Perfusions in Liver Transplantation: The Evidence‐Based Position Paper of the Italian Society of Organ and Tissue Transplantation
2020
The use of machine perfusion (MP) in liver transplantation (LT) is spreading worldwide. However, its efficacy has not been demonstrated, and its proper clinical use has far to go to be widely implemented. The Società Italiana Trapianti d’Organo (SITO) promoted the development of an evidence-based position paper. A 3-step approach has been adopted to develop this position paper. First, SITO appointed a chair and a cochair who then assembled a working group with specific experience of MP in LT. The Guideline Development Group framed the clinical questions into a patient, intervention, control, and outcome (PICO) format, extracted and analyzed the available literature, ranked the quality of th…
Radio network aspects
2006
Publisher Summary This chapter reviews the mobile radio access network reference scenarios (MORANS)—used to study the performance of the radio cellular networks related to UMTS and the methodologies for the radio network performance evaluation, including the theoretical connectivity models,. It discusses the techniques for radio network optimization such as the packet scheduling for cellular systems or system capacity maximization through the use of multiple antennas. . In order to perform system simulations, reference values for the main parameters characterizing a WCDMA network, are required. MORANS is used for the identification of such parameters. The parameters are classified in two gr…
UMTS radio networks
2006
Publisher Summary This chapter reviews the contributions to the UMTS radio network planning, with the optimization being provided from COST 273 and the real-time tuning, which is related to RRM. The results on UTRAN performance evaluation by the means of simulation tools are also discussed. The UMTS planning includes processes like: the propagation and traffic models, the aspects of parameter planning, and the automatic planning algorithms. An accurate ray-tracing model integrated in a UMTS-capable planning tool allows the radio network planner to reach optimal numbers for the BS deployment and configuration while meeting the service level requirements. Ray tracing can identify the problem …
Additional file 1 of Mechanical ventilation parameters in critically ill COVID-19 patients: a scoping review
2021
Additional file 1. Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) Checklist. Description of data: compiled PRISMA-ScR checklist.
ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19
2022
The International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC) COVID-19 dataset is one of the largest international databases of prospectively collected clinical data on people hospitalized with COVID-19. This dataset was compiled during the COVID-19 pandemic by a network of hospitals that collect data using the ISARIC-World Health Organization Clinical Characterization Protocol and data tools. The database includes data from more than 705,000 patients, collected in more than 60 countries and 1,500 centres worldwide. Patient data are available from acute hospital admissions with COVID-19 and outpatient follow-ups. The data include signs and symptoms, pre-existing como…
Respiratory support in patients with severe COVID-19 in the International Severe Acute Respiratory and Emerging Infection (ISARIC) COVID-19 study: a …
2022
Invasive mechanical ventilation; COVID-19; Critical care Ventilación mecánica invasiva; COVID-19; Cuidado crítico Ventilació mecànica invasiva; COVID-19; Atenció crítica Background Up to 30% of hospitalised patients with COVID-19 require advanced respiratory support, including high-flow nasal cannulas (HFNC), non-invasive mechanical ventilation (NIV), or invasive mechanical ventilation (IMV). We aimed to describe the clinical characteristics, outcomes and risk factors for failing non-invasive respiratory support in patients treated with severe COVID-19 during the first two years of the pandemic in high-income countries (HICs) and low middle-income countries (LMICs). Methods This is a multin…
Association of country income level with the characteristics and outcomes of critically ill patients hospitalized with acute kidney injury and COVID-…
2023
Introduction Acute kidney injury (AKI) has been identified as one of the most common and significant problems in hospitalized patients with COVID-19. However, studies examining the relationship between COVID-19 and AKI in low- and low-middle income countries (LLMIC) are lacking. Given that AKI is known to carry a higher mortality rate in these countries, it is important to understand differences in this population. Methods This prospective, observational study examines the AKI incidence and characteristics of 32,210 patients with COVID-19 from 49 countries across all income levels who were admitted to an intensive care unit during their hospital stay. Results Among patients with COVID-19 ad…