0000000000599758

AUTHOR

Alessio Cerquaglia

showing 2 related works from this author

Reply to Comment on: 'Corneal confocal scanning laser microscopy in patients with dry eye disease treated with topical cyclosporine'

2017

Reply to Comment on: ‘Corneal confocal scanning laser microscopy in patients with dry eye disease treated with topical cyclosporine’

0301 basic medicineLaser Microscopymedicine.medical_specialtygenetic structuresConfocalAdministration TopicaleducationDry Eye SyndromesOphthalmic SolutionCornea03 medical and health sciencesImmunosuppressive Agent0302 clinical medicineOphthalmologyCorneaMicroscopyCorrespondenceMedicineHumansIn patientOphthalmology; Sensory Systems; Dry Eye; Corneal confocal scanning laser microscopyCorneal confocal scanning laser microscopyMicroscopy Confocalbusiness.industryDry Eyeeye diseasesSensory SystemsOphthalmology030104 developmental biologyOphthalmic solutionsmedicine.anatomical_structure030221 ophthalmology & optometryCyclosporineDry Eye Syndromessense organsOphthalmic SolutionsbusinessImmunosuppressive AgentsHuman
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Corneal confocal scanning laser microscopy in patients with dry eye disease treated with topical cyclosporine

2017

Purpose To investigate the effect of cyclosporine on corneal ultrastructure and on major signs and symptoms of patients with dry eye disease.Patients and methods In this prospective cohort study, patients with dry eye disease were treated with a drop of cyclosporine 0.05% twice daily. Clinical evaluation was carried out at baseline and at months 1, 3, and 6. All patients completed the Ocular Surface Disease Index (OSDI) questionnaire, and tear film break-up time (BUT), fluorescein and lissamine green staining, and Schirmer test were carried out. In vivo confocal microscopy was also performed and epithelial cellular density, keratocyte activation, and subbasal plexus morphology were assessed…

AdultMale0301 basic medicinemedicine.medical_specialtyAdministration TopicalConfocalDry Eye SyndromesGlaucomaCell CountOphthalmic SolutionFollow-Up StudieCorneaImmunosuppressive Agent03 medical and health scienceschemistry.chemical_compound0302 clinical medicineOphthalmologyCorneamedicineOcular Surface Disease IndexFluoresceinProspective cohort studyAgedMicroscopy Confocalbusiness.industryMiddle Agedmedicine.diseaseStainingProspective StudieOphthalmologyTreatment Outcome030104 developmental biologymedicine.anatomical_structureNerve FiberchemistryCyclosporine030221 ophthalmology & optometryFemalebusinessDry Eye SyndromeHumanEye
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