0000000000600124

AUTHOR

Lidia Monzo-beltran

showing 4 related works from this author

The Effect of Moderate- Versus High-Intensity Resistance Training on Systemic Redox State and DNA Damage in Healthy Older Women

2018

This study investigated effects of a 16-week progressive resistance training program (RTP) with elastic bands at two different intensities on systemic redox state, DNA damage, and physical function in healthy older women. Methods: Participants were randomly assigned to the high-intensity group (HIGH; n = 39), moderate-intensity group (MOD; n = 31), or control group (CG; n = 23). The exercise groups performed an RTP twice a week with three to four sets of 6 (HIGH) or 15 (MOD) repetitions of six overall body exercises at a perceived exertion rate of 8–9 on the OMNI-Resistance Exercise Scale for use with elastic bands. Thiol redox state was determined by reduced glutathione (GSH), oxidized gl…

Agingmedicine.medical_specialtyDNA damageStrength trainingEstrès oxidatiuUrinemedicine.disease_causeRedox03 medical and health scienceschemistry.chemical_compound0302 clinical medicineInternal medicinemedicineHumansDeoxyguanosineAgedAged 80 and overResearch and TheoryResistance trainingResistance Training030229 sport sciencesGlutathioneMiddle AgedEntrenament (Esport)GlutathioneHealthy VolunteersExercise TherapyEndocrinologychemistryFemaleOxidation-Reduction030217 neurology & neurosurgeryOxidative stressDNA Damage
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One-year follow-up of clinical, metabolic and oxidative stress profile of morbid obese patients after laparoscopic sleeve gastrectomy. 8-oxo-dG as a …

2017

Obesity has grown worldwide over the last few decades. In its different degrees, obesity is accompanied by many clinical and biochemical alterations reflecting the pathological condition of various body tissues. Among the mechanisms underlying the pathogenesis of obesity and associated complications, oxidative stress (OS) may be playing an important role. In the present study, we have characterized at systemic level the degree of OS status in a group of morbid obese patients (BMI>40 kg/m2) at basal sate and its modulation during one year after bariatric surgery using the laparoscopic sleeve gastrectomy (LSG) technique. As compared with normal weight subjects matched in age, peripheral blood…

Male0301 basic medicinemedicine.medical_treatmentClinical Biochemistrymedicine.disease_causeBiochemistryAntioxidantsMorbid obesityLipid peroxidationchemistry.chemical_compound0302 clinical medicine8-oxo-78-2′-deoxyguanosinelcsh:QH301-705.5chemistry.chemical_classificationlcsh:R5-920biologyGlutathione peroxidaseMiddle AgedMalondialdehydeGlutathioneObesity Morbid8-Hydroxy-2'-Deoxyguanosine030220 oncology & carcinogenesisFemalelcsh:Medicine (General)Research PaperAdultmedicine.medical_specialtyUrinary systemSuperoxide dismutase03 medical and health sciencesGastrectomyInternal medicinemedicineHumansBariatric surgeryInsulinOrganic ChemistryDeoxyguanosineGlutathioneOxidative Stress030104 developmental biologyEndocrinologylcsh:Biology (General)chemistrybiology.proteinDNA damageLipid PeroxidationBiomarkersOxidative stressFollow-Up StudiesRedox Biology
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Urinary metals and metal mixtures and oxidative stress biomarkers in an adult population from Spain: The Hortega Study

2019

Introduction: Few studies have investigated the role of exposure to metals and metal mixtures on oxidative stress in the general population. Objectives: We evaluated the cross-sectional association of urinary metal and metal mixtures with urinary oxidative stress biomarkers, including oxidized to reduced glutathione ratio (GSSG/GSH), malondialdehyde (MDA), and 8‑oxo‑7,8‑dihydroguanine (8-oxo-dG), in a representative sample of a general population from Spain (Hortega Study). Methods: Urine antimony (Sb), barium (Ba), cadmium (Cd), chromium (Cr), cobalt (Co), copper (Cu), molybdenum (Mo), vanadium (V) and zinc (Zn) were measured by ICPMS in 1440 Hortega Study participants. Results: The geomet…

AdultMaleUrine metals010504 meteorology & atmospheric sciencesPopulationchemistry.chemical_elementUrineZinc010501 environmental sciencesPopulation-basedmedicine.disease_cause01 natural scienceschemistry.chemical_compoundChromiumMetal mixturesMalondialdehydeMetals HeavymedicineHumanseducationlcsh:Environmental sciences0105 earth and related environmental sciencesGeneral Environmental ScienceAgedlcsh:GE1-350Cadmiumeducation.field_of_studyDeoxyguanosineGlutathioneMiddle AgedMalondialdehydeGlutathioneCross-Sectional Studieschemistry8-Hydroxy-2'-DeoxyguanosineSpainOxidative stressEnvironmental PollutantsFemaleOxidative stressBiomarkersNuclear chemistryEnvironment International
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The Effectiveness of Glutathione Redox Status as a Possible Tumor Marker in Colorectal Cancer

2021

The role of oxidative stress (OS) in cancer is a matter of great interest due to the implication of reactive oxygen species (ROS) and their oxidation products in the initiation of tumorigenesis, its progression, and metastatic dissemination. Great efforts have been made to identify the mechanisms of ROS-induced carcinogenesis

Male0301 basic medicineColorectal cancermedicine.disease_causechemistry.chemical_compound0302 clinical medicineoxidative stressBiology (General)Spectroscopychemistry.chemical_classificationChemistryGeneral MedicineMiddle AgedGlutathioneComputer Science ApplicationsChemistrytumor markers030220 oncology & carcinogenesisFemaleGSSGColorectal NeoplasmsGSH redox stateOxidation-ReductionQH301-705.5colorectal cancerRedoxArticleCatalysisInorganic Chemistry03 medical and health sciencesBiomarkers TumorGSHmedicineHumansPhysical and Theoretical ChemistryQD1-999Molecular BiologyAgedGSSG/GSH redox stateTumor markerReactive oxygen speciesOrganic ChemistryCancerGlutathionemedicine.disease030104 developmental biologyCase-Control StudiesCancer researchReactive Oxygen SpeciesCarcinogenesisOxidative stressInternational Journal of Molecular Sciences
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