0000000000600225
AUTHOR
J.n.h. Reek
Supramolecular hydrogen-bonding tautomeric sulfonamido-phosphinamides: a perfect P-chirogenic memory
P-chirogenic, supramolecular hydrogen-bonding C1-symmetrical sulfonamido–phosphinamides (METAMORPhos) have been successfully prepared. They were all found to possess a characteristic prototropic equilibrium between the PIII and the PV tautomers that is slow on the NMR spectroscopic timescale. Despite the dynamic and reversible protonation of the P centre, the P-chirogenic information was found to be retained in the tautomerization process, even in a protic solvent environment. Several strategies to access the corresponding enantiopure compounds were investigated, such as diastereoselective crystallization, or enantioselective synthesis. It was possible to resolve such a class of chiral liga…
CCDC 836863: Experimental Crystal Structure Determination
Related Article: F.W.Patureau, M.A.Siegler, A.L.Spek, A.J.Sandee, S.Juge, S.Aziz, A.Berkessel, J.N.H.Reek|2012|Eur.J.Inorg.Chem.||496|doi:10.1002/ejic.201100811
CCDC 836862: Experimental Crystal Structure Determination
Related Article: F.W.Patureau, M.A.Siegler, A.L.Spek, A.J.Sandee, S.Juge, S.Aziz, A.Berkessel, J.N.H.Reek|2012|Eur.J.Inorg.Chem.||496|doi:10.1002/ejic.201100811