0000000000601702

AUTHOR

Ana Claudia Torrecilhas

showing 3 related works from this author

The future of Extracellular Vesicles as Theranostics – an ISEV meeting report

2020

ABSTRACT The utilization of extracellular vesicles (EVs) in clinical theranostics has rapidly advanced in the past decade. In November 2018, the International Society for Extracellular Vesicles (ISEV) held a workshop on “EVs in Clinical Theranostic”. Here, we report the conclusions of roundtable discussions on the current advancement in the analysis technologies and we provide some guidelines to researchers in the field to consider the use of EVs in clinical application. The main challenges and the requirements for EV separation and characterization strategies, quality control and clinical investigation were discussed to promote the application of EVs in future clinical studies.

0301 basic medicineEngineeringHistologytheranosticMeeting ReportFreeze thawingExtracellular vesiclesCa 19 9 antigen03 medical and health sciences0302 clinical medicineClinical investigationIn vitro studylcsh:QH573-671therapylcsh:Cytologybusiness.industryDietary intakeAntibody affinityCell BiologyExtracellular vesicles030104 developmental biology030220 oncology & carcinogenesisAntisense oligonucleotidesbiomarkerEngineering ethicsbusinessJournal of Extracellular Vesicles
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Minimal information for studies of extracellular vesicles 2018 (MISEV2018):a position statement of the International Society for Extracellular Vesicl…

2018

The last decade has seen a sharp increase in the number of scientific publications describing physiological and pathological functions of extracellular vesicles (EVs), a collective term covering various subtypes of cell-released, membranous structures, called exosomes, microvesicles, microparticles, ectosomes, oncosomes, apoptotic bodies, and many other names. However, specific issues arise when working with these entities, whose size and amount often make them difficult to obtain as relatively pure preparations, and to characterize properly. The International Society for Extracellular Vesicles (ISEV) proposed Minimal Information for Studies of Extracellular Vesicles ("MISEV") guidelines fo…

ectosomeectosomes; exosomes; extracellular vesicles; guidelines; microparticles; microvesicles; minimal information requirements; reproducibility; rigor; standardization; Histology; Cell Biology[SDV]Life Sciences [q-bio]minimal information requirementsectosomes; exosomes; extracellular vesicles; guidelines; microparticles; microvesicles; minimal information requirements; reproducibility; rigor; standardizationsize-exclusionectosomesMedicine and Health SciencesCELL-DERIVED MICROPARTICLESFIELD-FLOW FRACTIONATIONguidelinesrequirementscirculatingComputingMilieux_MISCELLANEOUSmicroparticlesManchester Cancer Research Centrelcsh:Cytologyextracellular vesicles; exosomes; ectosomes; microvesicles; minimal information requirements; guidelines; standardization; microparticles; rigor; reproducibilityPROSTATE-CANCERmicroparticleCell interactionmicrovesiclechromatographyPosition Paperextracellular vesiclesguidelineLife Sciences & Biomedicinemicrovesiclesectosomes exosomes extracellular vesicles guidelines microparticles microvesicles minimal information requirements reproducibility rigor standardizationMEMBRANE-VESICLESHistologyFETAL BOVINEEctosomes ; Exosomes ; Extracellular Vesicles ; Guidelines ; Microparticles ; Microvesicles ; Minimal Information Requirements ; Reproducibility ; Rigor ; StandardizationCIRCULATING MICROPARTICLES[SDV.BC]Life Sciences [q-bio]/Cellular Biologyexosomesddc:570exosomeSURFACE-PLASMON RESONANCEddc:610lcsh:QH573-671BiologyreproducibilitystandardizationInteracció cel·lularScience & TechnologyResearchInstitutes_Networks_Beacons/mcrcCell BiologyrigorCell membranesHUMAN URINARY EXOSOMESPREANALYTICAL PARAMETERSminimal information requirementSIZE-EXCLUSION CHROMATOGRAPHY1182 Biochemistry cell and molecular biologyextracellular vesicleHuman medicineMembranes cel·lulars
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Highlights of the São Paulo ISEV workshop on extracellular vesicles in cross-kingdom communication

2017

In the past years, extracellular vesicles (EVs) have become an important field of research since EVs have been found to play a central role in biological processes. In pathogens, EVs are involved in several events during the host–pathogen interaction, including invasion, immunomodulation, and pathology as well as parasite–parasite communication. In this report, we summarised the role of EVs in infections caused by viruses, bacteria, fungi, protozoa, and helminths based on the talks and discussions carried out during the International Society for Extracellular Vesicles (ISEV) workshop held in São Paulo (November, 2016), Brazil, entitled Cross-organism Communication by Extracellular Vesicles:…

0301 basic medicineHistologyOtras Ciencias Biológicas030106 microbiologyINTERAÇÃO CELULARBiologyMeeting Reportinfectious diseasesExtracellular vesiclesArticleMicrobiology//purl.org/becyt/ford/1 [https]Ciencias Biológicas03 medical and health sciencesparasitic diseaseslcsh:QH573-671//purl.org/becyt/ford/1.6 [https]lcsh:Cytologycell communicationpathogensCell BiologyExtracellular vesiclesCell biology030104 developmental biologycell communication; Extracellular vesicles; infectious diseases; isolation; pathogens; Histology; Cell BiologyisolationCIENCIAS NATURALES Y EXACTAS
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