0000000000605673

AUTHOR

Uwe Haberkorn

showing 2 related works from this author

Influence of cell proportions and proliferation rates on FDG uptake in squamous-cell esophageal carcinoma: a PET study.

2008

We investigated the influence of cell proportions and proliferation activities on tumor maximum standard uptake value (SUV(max)) in patients with squamous-cell esophageal cancer (SCEC).Sixteen (16) patients with untreated SCEC were examined with (18)F-flourodeoxyglucose positron emission tomography (FDG-PET). The tumor SUV(max) were calculated. Tumors were resected by transthoracic esophagectomy. Tissues were stained with hematoxylin and eosin for the measurement of cell proportions and MIB-1 for measurement of proliferation indices (PIs). Tumor SUV and histologic data were related by using multiple linear regression analysis.The mean proportion of tumor cells in the tumor site was 58.1% (+…

MaleCancer ResearchPathologymedicine.medical_specialtyEsophageal NeoplasmsCellH&E stainStandardized uptake valueFluorodeoxyglucose F18medicineCarcinomaHumansRadiology Nuclear Medicine and imagingAgedCell ProliferationCell SizePharmacologymedicine.diagnostic_testbusiness.industryFdg uptakeGeneral MedicineEsophageal cancerMiddle Agedmedicine.diseaseImmunohistochemistrymedicine.anatomical_structureOncologyPositron emission tomographyPositron-Emission TomographyCarcinoma Squamous CellMultiple linear regression analysisFemalebusinessCancer biotherapyradiopharmaceuticals
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The effect of amifostine or IMRT to preserve the parotid function after radiotherapy of the head and neck region measured by quantitative salivary gl…

2008

Purpose: In this retrospective study, two approaches to preserve the parotid function after radiotherapy (RT) were compared: application of the radioprotective agent amifostine during RT and parotid sparing intensity-modulated radiotherapy (IMRT). Patients and methods: Patients were qualified for this analysis if (1) both parotid glands received a radiation dose of P50 Gy using conventional radiotherapy techniques (cRT) or if they received a parotid sparing IMRT as alternative, if (2) salivary gland scintigraphies before and after RT were performed, and if (3) a normal parotid function was present before RT. Quantitative salivary gland scintigraphy was used to assess the parotid gland funct…

AdultMaleAdolescentmedicine.medical_treatmentRadiation-Protective AgentsRadiation DosageXerostomiaAmifostinestomatognathic systemSalivary gland scintigraphymedicineHumansParotid GlandRadiology Nuclear Medicine and imagingRadiation InjuriesRadionuclide ImagingHead and neckAgedRetrospective StudiesAged 80 and overSalivary glandbusiness.industryHead and neck cancerRetrospective cohort studyHematologyAmifostineMiddle Agedmedicine.diseaseParotid glandRadiation therapystomatognathic diseasesmedicine.anatomical_structureOncologyHead and Neck NeoplasmsFemaleRadiotherapy Intensity-ModulatedbusinessNuclear medicinemedicine.drugRadiotherapy and Oncology
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