0000000000606315

AUTHOR

Christoph Brehm

showing 2 related works from this author

CRT-727 Percutaneous Balloon Atrial Septostomy for Direct Left Heart Decompression in Patients on Extra Corporeal Membrane Oxygenation

2014

Severe myocardial dysfunction and added afterload from the Extra Corporeal Membrane Oxygenation (ECMO) arterial cannula may lead to significant rise in left ventricular (LV) end-diastolic and left atrial (LA) pressures. This may result in ischemia, lower likelihood of ventricular recovery and hence

musculoskeletal diseasesmedicine.medical_specialtyPercutaneousbusiness.industryDecompressionIschemiaOxygenationmedicine.diseaseBalloon atrial septostomysurgical procedures operativeAfterloadLeft atrialInternal medicineAnesthesiacardiovascular systemCardiologymedicineIn patientcardiovascular diseasesbusinessCardiology and Cardiovascular MedicineJACC: Cardiovascular Interventions
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Identification of Differentially Expressed Genes in Papillary Thyroid Carcinomas With and Without Rearrangements of the Tyrosine Kinase Receptors RET…

2005

Background The transforming capacities of RET and/or NTRK1 chimeric oncogenes as well as the molecular background of non-rearranged papillary thyroid carcinomas (PTCs) remain to be elucidated. To assess altered gene expression, we examined PTCs with and without tyrosine kinase receptor rearrangements by mRNA differential display (DD). Materials and methods Six of 13 PTCs examined harbored RET chimeras (3× RET/PTC1, 1× RET/PTC3) and/or NTRK1 chimeras (2× trk, 1× TRK-T3, 2 unknown TRK hybrids). The method of DD analysis was refined by a novel fragment-recovery technique using a high-performance fluorescence scanner. Results Of 500 up- or down-regulated mRNA transcripts, 19 selected fragments …

AdultMaleAdolescentendocrine system diseasesDown-RegulationBiologyReceptor tyrosine kinaseGene expressionHumansThyroid NeoplasmsReceptor trkAGeneAgedCell ProliferationGene RearrangementRegulation of gene expressionGene Expression ProfilingProto-Oncogene Proteins c-retGene rearrangementMiddle AgedCarcinoma PapillaryUp-RegulationGene Expression Regulation NeoplasticGene expression profilingTumor progressionTrk receptorDisease ProgressionCancer researchbiology.proteinFemaleSurgeryJournal of Surgical Research
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