Polyreaktionen in orientierten Medien, 4. Fotoreaktionen von Fumar- und Maleinsäurederivaten in Multischichten

Nitric oxide-mediated inhibition of androgen receptor activity: possible implications for prostate cancer progression.

Chronic inflammation increases the risk of cancer and many cancers, including prostate cancer, arise at sites of chronic inflammation. Inducible nitric oxide synthase (iNOS) is an enzyme dominantly expressed during inflammatory reactions. Although synthesis of high amounts of nitric oxide (NO) by iNOS has been demonstrated in pathophysiological processes, such as acute or chronic inflammation, autoimmune diseases or tumorigenesis, the role of iNOS activity in most of these diseases is poorly understood. Analysing prostate cancer biopsies by immunohistochemistry we found iNOS protein expression in tumor cells strongly paralleled by nitrotyrosine suggesting that iNOS is fully active. In vitro…

Probleme der Stadieneinteilung beim fortgeschrittenen Blasentumor

Eine bis zu 50% reichende Unterschatzung der Blasencarcinome in den Stadien pTa bis hin zum Stadium pT3a, eine uber 50% reichende Uberschatzung der Stadien pT3b und pT4 und eine richtige Aussage in nur 44% der Falle kennzeichnen die Problematik der exakten klinischen Stadienerfassung von Blasentumoren in der „Vor-CT-Aera“ [2].