0000000000610049

AUTHOR

Barbara Nicolas

showing 2 related works from this author

Autoimmune Myopathy Due To Statin Treatment In An Elderly Woman

2014

International audience

medicine.medical_specialty[SCCO]Cognitive sciencebusiness.industryInternal medicinePhysical therapyMedicine[ SCCO ] Cognitive scienceGeriatrics and GerontologyStatin treatmentbusinessAutoimmune myopathyTHERAPYComputingMilieux_MISCELLANEOUS
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Efficacy and safety of dapsone as second line therapy for adult immune thrombocytopenia: A retrospective study of 42 patients.

2017

Dapsone is recommended as a second line therapy in immune thrombocytopenia (ITP), but is underused because of its potential side effects. The medical charts of 42 ITP patients treated with dapsone (100 mg/day) were retrospectively reviewed in order to assess its efficacy and safety in daily clinical practice. The overall response rate was 54.8% (n = 22, with a complete response in 38.1%) with a median time to response of 29 days (24-41 days). Patients with complete response had shorter disease duration whereas no difference was observed between responders and non-responders regarding age, sex or previous treatments received. Importantly, after dapsone withdrawal, a sustained response was ob…

Adultmedicine.medical_specialtymedicine.medical_treatmentSplenectomylcsh:Medicine030204 cardiovascular system & hematologyDapsone03 medical and health sciences0302 clinical medicineInternal medicinemedicineHumansAdverse effectlcsh:ScienceRetrospective StudiesSecond-line therapyPurpura Thrombocytopenic IdiopathicMultidisciplinarybusiness.industrylcsh:RRetrospective cohort studyImmune thrombocytopeniaSurgerySustained responseCohortlcsh:QbusinessDapsone030215 immunologymedicine.drugResearch ArticlePloS one
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