0000000000611936

AUTHOR

Rosa De Vincenzo

0000-0001-7408-0435

showing 3 related works from this author

Peritoneal HPV‐DNA test in cervical cancer (PIONEER study): A proof of concept

2020

The aim of this study was to investigate the prevalence of peritoneal human papillomavirus (HPV) infection in different clinical cervical cancer (CC) settings, and its association with potential clinical and/or histological factors. This is a single-center, prospective, observational study. Consecutive patients with newly diagnosed or recurrent/persistent CC, between March 2019 and April 2020, were included. A group of patients undergoing surgery for benign gynecological conditions was included as control group. All patients underwent HPV-DNA test in the cervix and in the peritoneal cavity simultaneously at time of surgery. Two-hundred seventy-two patients had cervical and peritoneal HPV te…

AdultHPVCancer Researchmedicine.medical_specialtyMultivariate analysiscervical cancergenotypemedicine.medical_treatmentUterine Cervical Neoplasmsprognostic factors.GastroenterologyHuman Papillomavirus DNA Tests03 medical and health sciencesPeritoneal cavity0302 clinical medicinegenotypesInternal medicineGenotypemedicineHumansProspective StudiesStage (cooking)Peritoneal CavityCervixAgedNeoplasm StagingAged 80 and overCervical cancerHuman papillomavirus 16Human papillomavirus 18business.industryHPV infectionprognostic factorsMiddle Agedperitoneummedicine.diseaseCervical conizationinfectionSettore MED/40 - GINECOLOGIA E OSTETRICIAmedicine.anatomical_structureOncology030220 oncology & carcinogenesisFemalebusinessInternational Journal of Cancer
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Protective Role of Conization Before Radical Hysterectomy in Early-Stage Cervical Cancer: A Propensity-Score Matching Study.

2021

Purpose: The purpose of this study was to assess the prognostic role and the perioperative outcomes of conization performed before radical hysterectomy in early-stage cervical carcinoma. Methods: This multicenter, retrospective observational cohort study included patients with FIGO 2009 stage IB1 cervical carcinoma treated with radical hysterectomy between June 2004 and June 2019. Patients were divided into two groups according to conization before radical surgery. One-to-one case–control matching was used to adjust the baseline characteristics. Results: A total of 332 patients were included after propensity matching (166, 50% in each group). Twenty-four of 166 (14.4%) and 142 of 166 (85.6%…

medicine.medical_specialtyConizationUterine Cervical NeoplasmsHysterectomy03 medical and health sciences0302 clinical medicineMedicineHumansRisk factorStage (cooking)Radical surgeryRadical HysterectomyNeoplasm StagingRetrospective StudiesCervical cancerbusiness.industryPerioperativemedicine.diseaseSurgeryNeoplasm RecurrenceSettore MED/40 - GINECOLOGIA E OSTETRICIALocalOncology030220 oncology & carcinogenesisPropensity score matchingCervical cancer030211 gastroenterology & hepatologySurgeryFemaleNeoplasm Recurrence LocalbusinessCohort studyAnnals of surgical oncologyREFERENCES
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HPV Vaccination: The Position Paper of the Italian Society of Colposcopy and Cervico-Vaginal Pathology (SICPCV)

2020

Human papillomavirus (HPV) related cervical cancer represents an issue of public health priority. The World Health Organization recommended the introduction of HPV vaccination in all national public programs. In Europe, vaccines against HPV have been available since 2006. In Italy, vaccination is recommended and has been freely offered to all young girls aged 11 years since 2008. Three prophylactic HPV vaccines are available against high- and low-risk genotypes. The quadrivalent vaccine contains protein antigens for HPV 6, 11, 16, and 18. The bivalent vaccine includes antigens for HPV 16 and 18. The nonavalent vaccine was introduced in 2014, and it targets HPV types 6, 11, 16, 18, 31, 33, 4…

medicine.medical_specialtyPathologycervical cancerprimary preventionImmunologylcsh:MedicineReviewHPV vaccinescervical intraepithelial neoplasiaCervical intraepithelial neoplasia03 medical and health sciences0302 clinical medicineDrug DiscoverymedicinePharmacology (medical)030212 general & internal medicineYoung adulthuman papillomavirusHPV vaccinePharmacologyColposcopyCervical cancermedicine.diagnostic_testbusiness.industryPublic healthlcsh:Rmedicine.diseaseVaccinationClinical trialSettore MED/40 - GINECOLOGIA E OSTETRICIAInfectious Diseases030220 oncology & carcinogenesisbusinessVaccines
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