0000000000615195

AUTHOR

Elena Pozzecco

showing 2 related works from this author

Alveolar nitric oxide and asthma control in mild untreated asthma

2012

Background The role of the peripheral airways in asthma is increasingly being recognized as a potential target for the achievement of optimal control of the disease. We postulated that the inflammatory changes of the small airways are implicated in the lack of asthma control in mild asthma. Objective To test this hypothesis, we measured the alveolar fraction of exhaled NO (C alv NO) in patients with mild asthma with different levels of control of symptoms. Methods Seventy-eight patients with asthma (35 men, age, 37 ± 15 years; FEV 1 percentage of predicted, 100% ± 9%) were studied. Asthma control was assessed by using the Asthma Control Test (ACT). Measurements of exhaled NO at multiple con…

AdultMalemedicine.medical_specialtyVital capacityImmunologySettore MED/10 - Malattie Dell'Apparato RespiratorioNitric OxideGastroenterologyNitric oxideYoung Adultchemistry.chemical_compoundFEV1/FVC ratioAsthma controlInternal medicinemedicineHumansImmunology and AllergyYoung adultAsthmabusiness.industryExhalationmedicine.diseaseAsthmaRespiratory Function Testsrespiratory tract diseaseschemistryExhalationAnesthesiaFemalebusinessAsthma Control TestJournal of Allergy and Clinical Immunology
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Is Health-Related Quality of Life Associated with Upper and Lower Airway Inflammation in Asthmatics?

2013

Background.Allergic diseases impair health-related quality of life (HR-QoL). However, the relationship between airway inflammation and HR-QoL in patients with asthma and rhinitis has not been fully investigated. We explored whether the inflammation of upper and lower airways is associated with HR-QoL.Methods.Twenty-two mild allergic asthmatics with concomitant rhinitis (10 males, 38 ± 17 years) were recruited. The Rhinasthma was used to identify HR-QoL, and the Asthma Control Test (ACT) was used to assess asthma control. Subjects underwent lung function and exhaled nitric oxide (eNO) test, collection of exhaled breath condensate (EBC), and nasal wash.Results.The Rhinasthma Global Summary sc…

AdultMaleQuality of lifeArticle SubjectAsthma; Quality of life; Airway inflammationlcsh:MedicineInflammationSettore MED/10 - Malattie Dell'Apparato RespiratorioNitric OxideGeneral Biochemistry Genetics and Molecular BiologyNitric oxideAllergic inflammationchemistry.chemical_compoundSurveys and QuestionnairesmedicineHumansExhaled breath condensateRespiratory systemLungRespiratory Function Tests; Questionnaires; Humans; Quality of Life; Asthma; Health; Inflammation; Nitric Oxide; Lung; Adult; Pulmonary Alveoli; Biological Markers; Female; MaleAsthmaRespiratory Function TestInflammationLungGeneral Immunology and Microbiologybusiness.industryQuestionnairelcsh:RGeneral Medicinerespiratory systemmedicine.diseaseAsthmaRespiratory Function Testsrespiratory tract diseasesPulmonary Alveolimedicine.anatomical_structurechemistryHealthImmunologyExhaled nitric oxideBiological MarkerClinical StudyFemalemedicine.symptombusinessBiomarkersHumanAirway inflammationBioMed Research International
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