0000000000617029
AUTHOR
L Stafford
PE-CVD with organometallic precursors: contribution of aerosol assisted processes
International audience; PE-CVD is widely used to deposit inorganic thin films. For example, a lot of different precursors (TEOS, HMDSO, HMDS, TMS, etc.) has been used for organosilicon or silica-like coatings. In contrast, only few studies are using organometallic precursors. Indeed, such molecules are generally unstable, pyrophoric and highly reactive with air and/or oxygen. Aerosol-assisted processes are able to avoid these problems. Indeed, diluted in organic solvents, it enables to inject droplets of organometallic precursor charged liquids. This contribution aims to report first results obtained with nickel-or zinc-based organometallic precursors. Using a pulsed injection of the liquid…
Edoxaban versus warfarin for the treatment of symptomatic venous thromboembolism
BackgroundWhether the oral factor Xa inhibitor edoxaban can be an alternative to warfarin in patients with venous thromboembolism is unclear. MethodsIn a randomized, double-blind, noninferiority study, we randomly assigned patients with acute venous thromboembolism, who had initially received heparin, to receive edoxaban at a dose of 60 mg once daily, or 30 mg once daily (e.g., in the case of patients with creatinine clearance of 30 to 50 ml per minute or a body weight below 60 kg), or to receive warfarin. Patients received the study drug for 3 to 12 months. The primary efficacy outcome was recurrent symptomatic venous thromboembolism. The principal safety outcome was major or clinically re…