0000000000624060

AUTHOR

Fatima De La Cruz

showing 2 related works from this author

Characteristics and management of primary and other immune thrombocytopenias: Spanish registry study

2017

The natural history and its modulation by treatments administered for immune thrombocytopenia (ITP) in the clinical practice remains unknown. In addition, little information is available on the characteristics and management of ITP in Spain. We conducted an observational, multicenter, registry in 70 Hematology Services from Spain between 2009 and 2011, which included children from 2 months of age and adults with primary ITP or another ITP diagnosed within the last 6 months (platelet count [PC]  484 patients were included (median [Q1, Q3] age 52 [29,74] years, 87.6% adults), 56% women, 10.5% with secondary ITP. Median (Q1, Q3) PC at diagnosis was 12 × 109/l (4, 32); 72% of patients had bleed…

MalePediatricsRegistry studyComorbidity030204 cardiovascular system & hematologycorticosteroids0302 clinical medicineAdrenal Cortex Hormonesimmune system diseaseshemic and lymphatic diseasesRegistriesChildresponseHematologyDisease ManagementImmunoglobulins IntravenousHematologyMiddle AgedClinical PracticeNatural historyPhenotypeTreatment OutcomeIntravenous ImmunoglobulinsChild PreschoolFemaleAlgorithmsAdultmedicine.medical_specialtyAdolescentHemorrhageintravenous immunoglobulinsYoung Adult03 medical and health sciencesImmune systemInternal medicinemedicineHumansAgedPurpura Thrombocytopenic IdiopathicPlatelet Countbusiness.industryInfantImmune thrombocytopeniaImmune thrombocytopeniaSpainObservational studybusinessBiomarkers030215 immunologyHematology
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Brentuximab Vedotin Plus ESHAP (BRESHAP) Versus ESHAP As Salvage Strategy for Patients with Primary Refractory or Relapsed Classical Hodgkin's Lympho…

2021

Abstract Introduction. Patients with relapsed/refractory classical Hodgkin's lymphoma (RRHL) still represent a therapeutic challenge. Consolidation with autologous stem cell transplantation (auto-HCT) is the standard of care in this setting. The achievement of a metabolic complete remission (mCR) with salvage chemotherapy (CT) improves long-term outcome after auto-HCT. The introduction of new drugs has significantly changed the landscape of RRHL. Our cooperative group (GELTAMO) has already demonstrated that brentuximab vedotin (BV) + ESHAP (BRESHAP, García-Sanz R et al, Ann Oncol 2019) is able to achieve a mCR rate of 70% before auto-HCT in patients with RRHL. Nevertheless, the superiority …

Oncologymedicine.medical_specialtybusiness.industryImmunologyCell BiologyHematologyBiochemistryClassical Hodgkin's LymphomaClinical trialRefractoryInternal medicineMedicinebusinessBrentuximab vedotinESHAPmedicine.drugBlood
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