0000000000630757

AUTHOR

Iris Grunwald

0000-0002-3404-7590

showing 3 related works from this author

Second asymptomatic carotid surgery trial (ACST-2): a randomised comparison of carotid artery stenting versus carotid endarterectomy.

2021

Summary Background Among asymptomatic patients with severe carotid artery stenosis but no recent stroke or transient cerebral ischaemia, either carotid artery stenting (CAS) or carotid endarterectomy (CEA) can restore patency and reduce long-term stroke risks. However, from recent national registry data, each option causes about 1% procedural risk of disabling stroke or death. Comparison of their long-term protective effects requires large-scale randomised evidence. Methods ACST-2 is an international multicentre randomised trial of CAS versus CEA among asymptomatic patients with severe stenosis thought to require intervention, interpreted with all other relevant trials. Patients were eligib…

Malemedicine.medical_specialtyTime FactorsTime Factormedicine.medical_treatmentCarotid StenosiMEDLINECarotid endarterectomyRate ratioRisk AssessmentAsymptomaticlaw.inventionRandomized controlled triallawRisk Factorscarotid artery stenting (CAS); carotid endarterectomy (CEA)StentmedicineHumansCarotid StenosisStrokeEndarterectomyAgedEndarterectomy Carotidbusiness.industrycarotid arteryRisk FactorArticlesGeneral Medicinetrialmedicine.diseaseSettore MED/22 - CHIRURGIA VASCOLARESurgeryStrokeStenosisTreatment Outcomecarotid artery stenting (CAS)Settore MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLAREFemaleStentsHuman medicinemedicine.symptomcarotid endarterectomy (CEA)businessHumanLancet (London, England)
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Permanent Pacemaker Lead Insertion Connected to an External Pacemaker Generator for Temporary Pacing After Transcatheter Aortic Valve Implantation.

2019

Abstract Background Outcomes after transcatheter aortic valve implantation (TAVI) have been demonstrated to be at least equivalent in the short term compared to surgical valve implantation (SAVI). However, Conduction abnormalities are more common after TAVI than SAVI and the need for permanent pacemaker implantation is more common after TAVI with the currently commercially available self-expanding valves than after SAVI. Temporary pacemaker implantation may be associated with inability to ambulate, lead migration or perforation and infection. Depending on the monitoring system, some arrhythmias may not be detected. We examined the feasibility and safety of permanent pacemaker lead implantat…

Malemedicine.medical_specialtyPacemaker ArtificialPerforation (oil well)Context (language use)030204 cardiovascular system & hematologySingle CenterPericardial effusionRisk AssessmentTranscatheter Aortic Valve Replacement03 medical and health sciences0302 clinical medicineElectric Power SuppliesRisk FactorsmedicineHumans030212 general & internal medicineLead (electronics)AgedRetrospective StudiesAged 80 and overbusiness.industryCardiac Pacing ArtificialAtrial fibrillationArrhythmias CardiacGeneral MedicineEquipment Designmedicine.diseaseSurgeryTreatment OutcomeFeasibility StudiesFemalePatient SafetyPermanent pacemakerCardiology and Cardiovascular MedicinebusinessAtrioventricular blockCardiovascular revascularization medicine : including molecular interventions
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Effects of a Feedback-Demanding Stroke Clock on Acute Stroke Management: A Randomized Study.

2023

Background and Purpose: This randomized study aimed to evaluate whether the use of a stroke clock demanding active feedback from the stroke physician accelerates acute stroke management. Methods: For this randomized controlled study, a large-display alarm clock was installed in the computed tomography room, where admission, diagnostic work-up, and intravenous thrombolysis occurred. Alarms were set at the following target times after admission: (1) 15 minutes (neurological examination completed); (2) 25 minutes (computed tomography scanning and international normalized ratio determination by point-of-care laboratory completed); and (3) 30 minutes (intravenous thrombolysis started). The resp…

Malemedicine.medical_specialtythrombolysisTime FactorsComputed Tomography Angiographymedicine.medical_treatment610law.inventionBrain IschemiaFeedbackPhysical medicine and rehabilitationRandomized controlled trialFibrinolytic AgentslawmedicineHumansActive feedbackThrombolytic TherapyAcute managementStrokeAcute strokeAgedAdvanced and Specialized NursingAged 80 and overbusiness.industryDisease ManagementThrombolysisMiddle Agedmedicine.diseaseStrokethrombectomyTissue Plasminogen ActivatorFemaleNeurology (clinical)Cardiology and Cardiovascular Medicinebusinessacute managementTomography X-Ray ComputedStroke
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