0000000000634376

AUTHOR

Massimo Franchi

showing 5 related works from this author

Predictive Score of Nodal Involvement in Endometrial Cancer Patients: A Large Multicentre Series

2021

Background: Sentinel lymph node (SLN) biopsy is considered the standard of care in early-stage endometrial cancer (EC). For SLN failure, a side-specific lymphadenectomy is recommended. Nevertheless, most hemipelvises show no nodal involvement. The authors previously published a predictive score of lymphovascular involvement in EC. In case of a negative score (value 3–4), the risk of nodal metastases was extremely low. This multicenter study aimed to analyze a predictive score of nodal involvement in EC patients. Methods: The study enrolled patients with EC who had received comprehensive surgical staging with nodal assessment. A preoperative predictive score of nodal involvement was calculat…

medicine.medical_specialtymedicine.medical_treatmentSentinel lymph nodeLogistic regressionBiopsyHumansMedicineEndometrial NeoplasmNeoplasm Stagingmedicine.diagnostic_testbusiness.industrySentinel Lymph Node BiopsyEndometrial cancerArea under the curveLymph NodeLymphatic MetastasiOdds ratiomedicine.diseaseConfidence intervalEndometrial NeoplasmsOncologyLymphatic MetastasisLymph Node ExcisionSurgeryLymphadenectomyFemaleLymph NodesRadiologySentinel Lymph NodebusinessHuman
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Primary site disease and recurrence location in ovarian cancer patients undergoing primary debulking surgery vs. interval debulking surgery

2020

Introduction: The natural history and patterns of ovarian cancer (OC) relapse are still unclear. Recurrent disease can be peritoneal, parenchymal, or nodal. This study aims to analyze the location and pattern of OC recurrence according to the primary site of disease and to the type of surgical approach used. Material and methods: All OC patients underwent primary debulking surgery (PDS) or interval debulking surgery (IDS), with 2014 FIGO stage III-IV, and with platinum-sensitive recurrence were included in the study. Primary disease location and site of recurrences were divided into peritoneal, parenchymal, and nodal, according to the presence of peritoneal carcinomatosis, parenchymal metas…

Adultmedicine.medical_specialtyDiseaseMetastasis03 medical and health sciences0302 clinical medicineOvarian cancerRecurrenceMedicineHumans030212 general & internal medicineStage (cooking)Nodal involvementAgedOvarian Neoplasmsbusiness.industryGeneral MedicineCytoreduction Surgical ProceduresMiddle Agedmedicine.diseaseDebulkingSite of recurrencePeritoneal carcinomatosisSurgeryNatural historyNeoplasm RecurrenceOncologyLocalPrimary site location030220 oncology & carcinogenesisSurgeryFemaleNeoplasm Recurrence LocalPattern of recurrencebusinessOvarian cancer
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Risk factors associated with adverse fetal outcomes in pregnancies affected by Coronavirus disease 2019 (COVID-19): a secondary analysis of the WAPM …

2020

Abstract Objectives To evaluate the strength of association between maternal and pregnancy characteristics and the risk of adverse perinatal outcomes in pregnancies with laboratory confirmed COVID-19. Methods Secondary analysis of a multinational, cohort study on all consecutive pregnant women with laboratory-confirmed COVID-19 from February 1, 2020 to April 30, 2020 from 73 centers from 22 different countries. A confirmed case of COVID-19 was defined as a positive result on real-time reverse-transcriptase-polymerase-chain-reaction (RT-PCR) assay of nasal and pharyngeal swab specimens. The primary outcome was a composite adverse fetal outcome, defined as the presence of either abortion (pre…

COVID-19 VaccineInfectious Disease TransmissionPerinatal DeathAbortionClinical Laboratory TechniqueMiscarriageCohort Studies0302 clinical medicineCOVID-19 TestingPregnancyRisk Factors3123 Gynaecology and paediatricsSecondary analysisPerinatal medicineAbortion SpontaneouMedicineVertical030212 general & internal medicineViralPregnancy Complications Infectiouscoronavirus; perinatal morbidity; perinatal mortality; covid-19Coronavirus; perinatal morbidity; perinatal mortality; Abortion Spontaneous; COVID-19; COVID-19 Testing; COVID-19 Vaccines; Clinical Laboratory Techniques; Cohort Studies; Coronavirus Infections; Female; Gestational Age; Humans; Infant Newborn; Infant Premature; Infectious Disease Transmission Vertical; Pandemics; Pneumonia Viral; Pregnancy; Pregnancy Complications Infectious; Pregnancy Outcome; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; SARS-CoV-2; Betacoronavirus; Fetal Death; Perinatal Deathperinatal morbidity030219 obstetrics & reproductive medicineObstetricsReverse Transcriptase Polymerase Chain ReactionInfectiousPregnancy OutcomeGestational ageObstetrics and Gynecology3. Good healthSettore MED/40perinatal mortalityGestationFemaleCoronavirus InfectionsInfant PrematureHumanmedicine.medical_specialtyCOVID-19 VaccinesCoronavirus disease 2019 (COVID-19)CoronaviruPneumonia ViralSocio-culturaleGestational AgeIntrauterine deviceCoronavirus; perinatal morbidity; perinatal mortality03 medical and health sciencesBetacoronavirusPARVOVIRUS B19 INFECTIONCoronavirus perinatal morbidity perinatal mortalityHumansAdverse effectPrematurePandemicsFetal DeathPregnancyFetusBetacoronaviruPandemicCoronavirus Infectionbusiness.industryClinical Laboratory TechniquesSARS-CoV-2Risk FactorSpontaneousMORTALITYInfant NewbornAbortionCOVID-19InfantOdds ratioPneumoniamedicine.diseaseNewbornInfectious Disease Transmission VerticalAbortion SpontaneousPregnancy ComplicationsCoronavirusPediatrics Perinatology and Child HealthPregnancy Complications InfectiouCohort StudiebusinessCoronavirus; perinatal mortality; perinatal morbidityJournal of perinatal medicine
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Impact of covid-19 in gynecologic oncology: A nationwide italian survey of the sigo and mito groups

2020

Objective Coronavirus disease 2019 (COVID-19) has caused rapid and drastic changes in cancer management. The Italian Society of Gynecology and Obstetrics (SIGO), and the Multicenter Italian Trials in Ovarian cancer and gynecologic malignancies (MITO) promoted a national survey aiming to evaluate the impact of COVID-19 on clinical activity of gynecologist oncologists and to assess the implementation of containment measures against COVID-19 diffusion. Methods The survey consisted of a self-administered, anonymous, online questionnaire. The survey was sent via email to all the members of the SIGO, and MITO groups on April 7, 2020, and was closed on April 20, 2020. Results Overall, 604 particip…

International CooperationComputer-assisted web interviewingCOVID-19; Health Care Surveys; SARS-CoV-2 Infection; Surgical Oncology; Betacoronavirus; COVID-19; Coronavirus Infections; Female; Genital Neoplasms Female; Gynecologic Surgical Procedures; Gynecology; Humans; Infection Control; International Cooperation; Italy; Medical Oncology; Pandemics; Pneumonia Viral; SARS-CoV-2; Societies Medical; Surveys and Questionnaires; TriageMedical Oncology0302 clinical medicineGynecologic Surgical ProceduresSurgical oncologyGynecologic Surgical ProcedureSurveys and QuestionnairesPandemicHealth careMedicineInfection controlViralStatistics & numerical dataSurveySocieties Medical030219 obstetrics & reproductive medicineObstetrics and GynecologyGeneral MedicineSurgical OncologyOncologyItaly030220 oncology & carcinogenesisSARS-CoV-2 InfectionOriginal ArticleFemaleGenital NeoplasmsCoronavirus Infectionsmedicine.medical_specialtyGenital Neoplasms FemalePneumonia ViralGynecologic oncology03 medical and health sciencesBetacoronavirusMedicalHumansCOVID-19; Health Care Surveys; SARS-CoV-2 Infection; Surgical OncologyPandemicsInfection ControlBetacoronaviruPandemicbusiness.industryCoronavirus InfectionSARS-CoV-2COVID-19PneumoniaTriageSettore MED/40 - GINECOLOGIA E OSTETRICIAHealth Care SurveyGynecologyFamily medicineHealth Care SurveysTriagebusinessSocieties
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The Role of Micronutrients in Human Papillomavirus Infection, Cervical Dysplasia, and Neoplasm

2023

There is evidence that diet and nutrition are modifiable risk factors for several cancers. In recent years, attention paid to micronutrients in gynecology has increased, especially regarding Human papillomavirus (HPV) infection. We performed a review of the literature up until December 2022, aiming to clarify the effects of micronutrients, minerals, and vitamins on the history of HPV infection and the development of cervical cancer. We included studies having as their primary objective the evaluation of dietary supplements, in particular calcium; zinc; iron; selenium; carotenoids; and vitamins A, B12, C, D, E, and K. Different oligo-elements and micronutrients demonstrated a potential prote…

Human papillomaviruMicronutrients.Cervical cancerSettore MED/40 - Ginecologia E OstetriciaCervical dysplasiaCancer prevention
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