0000000000637310

AUTHOR

Tomas Holubec

showing 2 related works from this author

Early outcomes of patients with Marfan syndrome and acute aortic type A dissection.

2021

Acute aortic Stanford type A dissection remains a frequent and life-limiting event for patients with Marfan syndrome. Outcome results in this high-risk group are limited.The German Registry for Acute Aortic Dissection Type A collected the data of 56 centers between July 2006 and June 2015. Of 3385 patients undergoing operations for acute aortic Stanford type A dissection, 117 (3.5%) were diagnosed with Marfan syndrome. We performed a propensity score match comparing patients with Marfan syndrome with patients without Marfan syndrome in a 1:2 fashion.Patients with Marfan syndrome were significantly younger (42.9 vs 62.2 years; P  .001), predominantly male (76.9% vs 62.9%; P = .002), and less…

Pulmonary and Respiratory MedicineMarfan syndromeAortic archAortic dissectionmedicine.medical_specialtybusiness.industrySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Outcome analysismedicine.diseaseSurgeryMatched cohortmedicine.arteryPropensity score matchingmedicineSurgeryType a dissectionCardiology and Cardiovascular MedicinebusinessThe Journal of thoracic and cardiovascular surgery
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Prediction of mortality rate in acute type A dissection: the German Registry for Acute Type A Aortic Dissection score.

2020

Abstract OBJECTIVES The goal was to develop a scoring system to predict the 30-day mortality rate for patients undergoing surgery for acute type A aortic dissection on the basis of the German Registry for Acute Type A Aortic Dissection (GERAADA) data set and to provide a Web-based application for standard use. METHODS A total of 2537 patients enrolled in GERAADA who underwent surgery between 2006 and 2015 were analysed. Variable selection was performed using the R-package FAMoS. The robustness of the results was confirmed via the bootstrap procedure. The coefficients of the final model were used to calculate the risk score in a Web-based application. RESULTS Age [odds ratio (OR) 1.018, 95% …

Pulmonary and Respiratory Medicinemedicine.medical_specialty030204 cardiovascular system & hematologyPreoperative care03 medical and health sciences0302 clinical medicinePostoperative ComplicationsRisk FactorsMedicineHumansddc:610RegistriesAortic dissectionFramingham Risk Scorebusiness.industryMortality rateDissectionGeneral MedicineOdds ratiomedicine.diseaseConfidence intervalSurgeryCardiac surgeryAortic AneurysmDissectionAortic DissectionTreatment Outcome030228 respiratory systemAcute DiseaseSurgeryCardiology and Cardiovascular MedicinebusinessEuropean journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
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