0000000000638299

AUTHOR

Marta Villalba

showing 2 related works from this author

Clinical significance of Pneumocystis jirovecii DNA detection by real-time PCR in hematological patient respiratory specimens

2020

Microbiology (medical)Simplexvirusfood.ingredientbusiness.industryPneumonia PneumocystisDNAPneumocystis cariniiReal-Time Polymerase Chain Reactionmedicine.diseaseVirologyImmunocompromised Hostchemistry.chemical_compoundPneumoniaInfectious DiseasesfoodReal-time polymerase chain reactionchemistryPneumocystis jirovecii DNAHumansSimplexvirusMedicineClinical significanceRespiratory systembusinessDNAJournal of Infection
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Post-transplant cyclophosphamide and sirolimus based graft-versus-host disease prophylaxis after allogeneic stem cell transplantation for acute myelo…

2022

Post-transplant cyclophosphamide (PTCy) has emerged as a promising graft-versus-host disease (GvHD) prophylaxis in allogeneic hematopoietic stem cell transplantation (allo-HSCT). However, no studies have reported the efficacy of a GvHD prophylaxis based on PTCy with sirolimus (Sir-PTCy) in patients with acute myeloid leukemia (AML). In this retrospective study, we analyze the use of sirolimus in combination with PTCy, with or without mycophenolate mofetil (MMF), on 242 consecutive adult patients with AML undergoing a myeloablative first allo-HSCT from different donor types, in three European centers between January 2017 and December 2020. Seventy-seven (32%) patients received allo-HSCT from…

AdultSirolimusTransplantationBLOODTransplantation ConditioningCONDITIONING INTENSITYGVHD PROPHYLAXISHematopoietic Stem Cell TransplantationGraft vs Host Disease1ST COMPLETE REMISSIONHematologyMycophenolic AcidOPEN-LABELDIAGNOSISPatologiaHEMATOLOGIC MALIGNANCIESEUROPEAN-SOCIETYLeukemia Myeloid AcuteRISK INDEXHumansMARROW-TRANSPLANTATIONUnrelated DonorsCyclophosphamideRetrospective StudiesBone marrow transplantation
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