0000000000640567

AUTHOR

Vincenzo Puro

0000-0003-0291-4490

showing 2 related works from this author

COVID-19 in people living with HIV: Clinical implications of dynamics of the immune response to SARS-CoV-2.

2020

ABSTRACT Background Little evidence on COVID‐19 in people living with HIV (PLWH) is currently available. Material and Methods We reported clinical and viro‐immunological data of all HIV‐positive patients admitted to our centre with COVID‐19 from March 1 to May 12,2020. Results Overall, five patients were included: all were virologically‐suppressed on antiretroviral therapy and CD4+ count was >350 cell/mm3 in all but two patients. Although all patients had evidence of pneumonia on admission, only one developed respiratory failure. SARS‐CoV‐2‐RNA was never detected from nasopharyngeal swabs in two patients, whereas, in the others, viral clearance occurred within a maximum of 43 days. IgG prod…

Malemedicine.medical_treatmentHIV InfectionsAntibodies ViralSeverity of Illness IndexImmunoglobulin GPiperazinesimmune responseSARS‐CoV‐20302 clinical medicine030212 general & internal medicinebiologyCoinfectionImmunosuppressionMiddle AgedInfectious DiseasesAnti-Retroviral AgentsCytokinesRNA ViralReverse Transcriptase Inhibitors030211 gastroenterology & hepatologyFemaleAntibodyHeterocyclic Compounds 3-RingRiskPyridonesShort CommunicationShort CommunicationsTransgender PersonsProinflammatory cytokine03 medical and health sciencesImmune systemCOVID‐19VirologySeverity of illnessOxazinesmedicineHumansHIV Integrase InhibitorsTenofovirbusiness.industrySARS-CoV-2medicine.diseaseHIV infectionVirologyAntibodies NeutralizingCD4 Lymphocyte CountImmunity HumoralCOVID-19 Drug TreatmentPneumoniaRespiratory failureImmunologybiology.proteinbusinessJournal of medical virology
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COVID-19 disease - Temporal analyses of complete blood count parameters over course of illness, and relationship to patient demographics and manageme…

2020

Background Detailed temporal analyses of complete (full) blood count (CBC) parameters, their evolution and relationship to patient age, gender, co-morbidities and management outcomes in survivors and non-survivors with COVID-19 disease, could identify prognostic clinical biomarkers. Methods From 29 January 2020 until 28 March 2020, we performed a longitudinal cohort study of COVID-19 inpatients at the Italian National Institute for Infectious Diseases, Rome, Italy. 9 CBC parameters were studied as continuous variables [neutrophils, lymphocytes, monocytes, platelets, mean platelet volume, red blood cell count, haemoglobin concentration, mean red blood cell volume and red blood cell distribu…

Erythrocyte IndicesMaleViral DiseasesNeutrophilsPhysiologyclinical biomarkersRomeDisease030204 cardiovascular system & hematologyCardiovascular MedicineCohort StudiesLeukocyte CountWhite Blood Cells0302 clinical medicineMedical ConditionsAnimal CellsMedicine and Health SciencesRenal Failure030212 general & internal medicineLongitudinal StudiesLymphocytesSurvivorsCOPDMultidisciplinarymedicine.diagnostic_testQRComplete blood countMiddle AgedPrognosisBody FluidsInfectious DiseasesBloodSettore MED/38 - PEDIATRIA GENERALE E SPECIALISTICAPhysiological Parameterscovid-19; blood cell count; clinical biomarkerscovid-19Cardiovascular DiseasesNephrologyMedicineFemaleCellular TypesAnatomyMean Platelet VolumeCohort studyResearch ArticlePlateletsmedicine.medical_specialtyScienceImmune CellsImmunologyCardiology03 medical and health sciencesInternal medicinemedicineHumansObesityMean platelet volumeDemographyInflammationBlood Cellsbusiness.industryBody WeightBiology and Life SciencesRed blood cell distribution widthCovid 19Cell Biologymedicine.diseaseObesityBlood CountsAnisocytosisblood cell countbusinessBiomarkers
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