0000000000641559
AUTHOR
Minas E. Lemonis
Genetic prediction of ICU hospitalization and mortality in COVID‐19 patients using artificial neural networks
There is an unmet need of models for early prediction of morbidity and mortality of Coronavirus disease-19 (COVID-19). We aimed to a) identify complement-related genetic variants associated with the clinical outcomes of ICU hospitalization and death, b) develop an artificial neural network (ANN) predicting these outcomes and c) validate whether complement-related variants are associated with an impaired complement phenotype. We prospectively recruited consecutive adult patients of Caucasian origin, hospitalized due to COVID-19. Through targeted next-generation sequencing, we identified variants in complement factor H/CFH, CFB, CFH-related, CFD, CD55, C3, C5, CFI, CD46, thrombomodulin/THBD, …
Novel fuzzy-based optimization approaches for the prediction of ultimate axial load of circular concrete-filled steel tubes
An accurate estimation of the axial compression capacity of the concrete-filled steel tubular (CFST) column is crucial for ensuring the safety of structures containing them and preventing related failures. In this article, two novel hybrid fuzzy systems (FS) were used to create a new framework for estimating the axial compression capacity of circular CCFST columns. In the hybrid models, differential evolution (DE) and firefly algorithm (FFA) techniques are employed in order to obtain the optimal membership functions of the base FS model. To train the models with the new hybrid techniques, i.e., FS-DE and FS-FFA, a substantial library of 410 experimental tests was compiled from openly availa…
Revealing the nature of metakaolin-based concrete materials using artificial intelligence techniques
In this study, a model for the estimation of the compressive strength of concretes incorporating metakaolin is developed and parametrically evaluated, using soft computing techniques. Metakaolin is a component extensively employed in recent decades as a means to reduce the requirement for cement in concrete. For the proposed models, six parameters are accounted for as input data. These are the age at testing, the metakaolin percentage in relation to the total binder, the water-to-binder ratio, the percentage of superplasticizer, the binder to sand ratio and the coarse to fine aggregate ratio. For training and verification of the developed models a database of 867 experimental specimens has …