0000000000643029

AUTHOR

David M.g. Halpin

showing 4 related works from this author

Tiotropium Respimat® Add-On To Inhaled Corticosteroids Improves Lung Function In Patients With Symptomatic Mild Asthma: Results From A Phase III Trial

2014

medicine.medical_specialtyRespimatbusiness.industryAnesthesiaImmunologyMild asthmaPhysical therapymedicineImmunology and AllergyInhaled corticosteroidsIn patientbusinessLung functionJournal of Allergy and Clinical Immunology
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Tiotropium add-on therapy reduces seasonal peaks of asthma worsening in adults with symptomatic severe asthma

2019

Despite the use of preferred controller therapies (including inhaled corticosteroids [ICS] with or without additional long-acting β2-agonists [LABAs]), a large proportion of patients with asthma have poor disease control, leaving them at risk of recurring symptoms and episodes of asthma exacerbations and worsening [1, 2]. Such problems can be triggered by many different environmental factors including pollutants, respiratory infections or allergens [3]. They may occur sporadically, but are often determined by seasons, mirroring seasonal patterns of allergen exposure and prevalence of respiratory viral infection [3, 4]. They can cause reduced quality of life, increase asthma burden [2, 3], a…

AdultPulmonary and Respiratory Medicinemedicine.medical_specialtySevere asthma03 medical and health sciences0302 clinical medicineQuality of life (healthcare)Administration InhalationmedicineHumans030212 general & internal medicineTiotropium BromideAsthmaWork productivitybusiness.industryConflict of interestmedicine.diseaseAsthmaBronchodilator AgentsAdd on therapy030228 respiratory systemFamily medicineAbsenteeismDrug Therapy CombinationSeasonsALLERGEN EXPOSUREbusinessEuropean Respiratory Journal
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ARIA���EAACI statement on asthma and COVID���19 (June 2, 2020)

2021

Artículo con numerosos autores sólo se mencionan el primero y el de la UAM

2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)AllergyStatement (logic)MedicinaSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)virusesImmunology610Settore MED/10 - Malattie Dell'Apparato Respiratoriomedicine.disease_cause03 medical and health sciences0302 clinical medicineastmaMedicine and Health SciencesmedicineHumansImmunology and Allergy030212 general & internal medicineLetters to the EditorLetter to the Editorudc:616.2AsthmaCoronavirusScience & Technologybusiness.industrySARS-CoV-2virus diseasesCOVID-19asthmamedicine.diseaseVirologyAsthma3. Good health030228 respiratory systemcovid-191107 ImmunologyAngiotensin-Converting Enzyme 2businessARIA-EAACILife Sciences & Biomedicine600 Technik Medizin angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
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The Effect of Tiotropium in Symptomatic Asthma Despite Low- to Medium-Dose Inhaled Corticosteroids: A Randomized Controlled Trial.

2014

BackgroundTiotropium, a once-daily long-acting anticholinergic bronchodilator, has demonstrated efficacy in patients with asthma who were symptomatic despite treatment with medium- to high-dose inhaled corticosteroids (ICS).ObjectiveThe objective of this study was to evaluate the efficacy and safety of once-daily tiotropium Respimat (5 μg or 2.5 μg), compared with placebo Respimat, as add-on therapy to low- to medium-dose ICS for adults with symptomatic asthma.MethodsA phase III, double-blind, placebo-controlled trial was conducted (NCT01316380). Adults with symptomatic asthma receiving low- to medium-dose ICS (200-400 μg budesonide or equivalent dose) and a pre-bronchodilator forced expira…

SpirometryBudesonideAdultMaleRespimatmedicine.drug_classSymptomaticAnticholinergicMildPlacebo03 medical and health sciences0302 clinical medicineBronchodilatorsAdrenal Cortex HormonesBronchodilatorControlAdministration InhalationImmunology and AllergyMedicineHumans030212 general & internal medicineTiotropium BromideBudesonideAnticholinergic; Asthma; Bronchodilators; Control; GINA; ICS; Mild; Respimat; Symptomatic; Tiotropium; Administration Inhalation; Adrenal Cortex Hormones; Adult; Asthma; Bronchodilator Agents; Budesonide; Disease Progression; Drug Combinations; Female; Humans; Male; Placebo Effect; Spirometry; Tiotropium Bromide; Treatment Outcome; Immunology and AllergyAsthmamedicine.diagnostic_testbusiness.industryTiotropiumTiotropium bromidemedicine.diseasePlacebo EffectGINAAsthmarespiratory tract diseasesRespimatBronchodilator AgentsDrug CombinationsTreatment OutcomeInhalation030228 respiratory systemTolerabilityICSSpirometryAnesthesiaAdministrationDisease ProgressionFemalebusinessmedicine.drugThe journal of allergy and clinical immunology. In practice
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