0000000000644603

AUTHOR

Simona Doniņa

showing 2 related works from this author

Management of a primary malignant melanoma of uterine cervix stage IVA patient with radical surgery and adjuvant oncolytic virus Rigvir® therapy: A c…

2020

Abstract Primary malignant melanoma of the uterine cervix is a rare disease with poor prognosis and high recurrence rate. We used Rigvir® as adjuvant therapy for a stage IVA patient. Tolerability, overall and progression‐free survival are good.

Oncologymedicine.medical_specialtyRigvirmedicine.medical_treatmentlcsh:MedicineCase ReportCase Reports030204 cardiovascular system & hematology03 medical and health sciences0302 clinical medicineInternal medicineAdjuvant therapymelanomaMedicineRadical surgeryStage (cooking)ECHO-7 virusoncolytic viruslcsh:R5-920business.industryMelanomalcsh:RGeneral Medicinemedicine.diseaseOncolytic virusTolerability030220 oncology & carcinogenesisoncologyECHO‐7 virusbusinesslcsh:Medicine (General)AdjuvantRare diseaseuterine cervixClinical Case Reports
researchProduct

Tumor-associated autoantibody signature for the early detection of gastric cancer

2012

Autoantibodies against tumor-associated antigens are very attractive biomarkers for the development of noninvasive serological tests for the early detection of cancer because of their specificity and stability in the sera. In our study, we applied T7 phage display-based serological analysis of recombinant cDNA expression libraries technique to identify a representative set of antigens eliciting humoral responses in patients with gastric cancer (GC), produced phage-antigen microarrays and exploited them for the survey of autoantibody repertoire in patients with GC and inflammatory diseases. We developed procedures for data normalization and cutoff determination to define sero-positive signal…

MaleSerumCancer ResearchMicroarrayBiologySensitivity and SpecificityAntigenAntigens NeoplasmStomach NeoplasmsBacteriophage T7Biomarkers TumormedicineHumansSerologic TestsEarly Detection of CancerAgedAutoantibodiesGene LibraryInflammationAutoantibodyArea under the curveCancerMiddle AgedMicroarray Analysismedicine.diseasePrimary tumorOncologyImmunologyBiomarker (medicine)FemaleGastritismedicine.symptomInternational Journal of Cancer
researchProduct