0000000000651127

AUTHOR

Lucie Vettoretti

showing 3 related works from this author

The impact of frailty on ICU and 30-day mortality and the level of care in very elderly patients (≥ 80 years)

2017

Purpose: Very old critical ill patients are a rapid expanding group in the ICU. Indications for admission, triage criteria and level of care are frequently discussed for such patients. However, most relevant outcome studies in this group frequently find an increased mortality and a reduced quality of life in survivors. The main objective was to study the impact of frailty compared with other variables with regards to short-term outcome in the very old ICU population. Methods: A transnational prospective cohort study from October 2016 to May 2017 with 30 days follow-up was set up by the European Society of Intensive Care Medicine. In total 311 ICUs from 21 European countries participated. Th…

MaleTime FactorsOutcome AssessmentFrail Elderly/statistics & numerical data[SDV]Life Sciences [q-bio]HSJ UCIPassiveCritical Care and Intensive Care MedicineFrailty/classification/diagnosis/mortality/therapySeverity of Illness IndexSeverity of illneElderly0302 clinical medicineQuality of lifeElderly; Frailty; ICU; Mortality; Octogenarians; Severity of illness; Aged 80 and over; Critical Illness; Europe; Euthanasia Passive; Female; Frail Elderly; Frailty; Geriatric Assessment; Humans; Intensive Care Units; Length of Stay; Male; Outcome Assessment Health Care; Proportional Hazards Models; Prospective Studies; Quality of Life; Severity of Illness Index; Time Factors; Hospital MortalityOutcome Assessment Health Care80 and overProspective StudiesHospital Mortality030212 general & internal medicineProspective cohort studyAged 80 and overeducation.field_of_studyddc:617FrailtyMortality rate[SDV] Life Sciences [q-bio]EuropeIntensive Care UnitsLength of Stay/statistics & numerical dataCohortIntensive Care Units/statistics & numerical dataCritical IllneFemaleSOFA scoreHumanmedicine.medical_specialtyOctogenariansTime FactorCritical IllnessFrail ElderlyIntensive Care UnitPopulationINTENSIVE-CARESeverity of illnessEurope/epidemiologyOutcome Assessment (Health Care)03 medical and health sciencesOctogenarianIntensive careSeverity of illnessJournal ArticlemedicineHumansCOHORTMortalityOctogenarinansIntensive care medicineeducationGeriatric AssessmentAgedProportional Hazards ModelsOLDEREuthanasiabusiness.industry030208 emergency & critical care medicineLength of StayEuthanasia PassiveHealth CareProspective StudieCritical Illness/mortalityUNITICUEmergency medicineProportional Hazards ModelQuality of LifebusinessIntensive Care Medicine
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Time to blood culture positivity: An independent predictor of infective endocarditis and mortality in patients with Staphylococcus aureus bacteraemia

2019

International audience; Objectives - Time to blood culture positivity (TTP), a routinely available parameter in automated blood culture systems, may be a proxy for infectious burden in patients with bloodstream infections. We aimed to study the association between TTP and infective endocarditis (IE), or death, in patients with Staphylococcus aureus bacteraemia. Methods - VIRSTA is a multicenter prospective cohort study that included all adult patients with S. aureus bacteraemia in eight university hospitals in France (2009-2011). We analyzed data from four centers which collected data on TTP. Regression models were used to study the association between TTP and definite IE (Duke-Li criteria)…

MaleMethicillin-Resistant Staphylococcus aureus0301 basic medicineMicrobiology (medical)Staphylococcus aureusbacteraemiamedicine.medical_specialtyTime FactorsMultivariate analysis030106 microbiologyBacteremiaIndependent predictormedicine.disease_cause03 medical and health sciences0302 clinical medicineInterquartile rangehemic and lymphatic diseasesInternal medicinemedicineHumansBlood cultureProspective Studies030212 general & internal medicinetime to blood culture positivityProspective cohort study[SDV.MP] Life Sciences [q-bio]/Microbiology and ParasitologyAgedmedicine.diagnostic_testinfective endocarditisbusiness.industryEndocarditis BacterialGeneral MedicineMiddle AgedStaphylococcal Infectionsrespiratory systemmedicine.diseasemortality3. Good health[SDV.MP]Life Sciences [q-bio]/Microbiology and ParasitologyInfectious DiseasesQuartileBlood CultureStaphylococcus aureusInfective endocarditisFemalebusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyClinical Microbiology and Infection
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Factors associated with 12 week case-fatality in Staphylococcus aureus bacteraemia: a prospective cohort study

2016

International audience; Staphylococcus aureus bacteraemia (SAB) is a frequent and deadly disease. Given the lack of a randomized trial, optimal first-line antibiotic treatment is still debated. Our aim was to identify prognostic factors in SAB patients and to analyse the impact of first-line antibiotics. The VIRSTA prospective cohort study was conducted in eight tertiary care centres in France. Consecutive incident adults in whom a blood culture drawn in participating centres grew S. aureus between April 2009 and October 2011 were prospectively followed for 12 weeks. Factors associated with 12-week case-fatality were identified by multivariate logistic regression. We enrolled 2091 patients …

0301 basic medicineMicrobiology (medical)Malemedicine.medical_specialtyStaphylococcus aureusmedicine.drug_class030106 microbiologyAntibioticsBacteremiaPenicillinsPrognostic factorsTertiary Care Centers03 medical and health sciencesInterquartile range[ SDV.MP ] Life Sciences [q-bio]/Microbiology and ParasitologyVancomycinInternal medicineCase fatality ratemedicineHumansBlood cultureProspective StudiesProspective cohort study[SDV.MP] Life Sciences [q-bio]/Microbiology and ParasitologyAgedAntistaphylococcal penicillinsCross Infectionmedicine.diagnostic_testbusiness.industrySeptic shockGeneral MedicineMiddle AgedStaphylococcal Infectionsmedicine.diseasePrognosisSurvival Analysis3. Good healthSurgeryInfectious Diseases[SDV.MP]Life Sciences [q-bio]/Microbiology and ParasitologyVancomycinBacteraemiaAntistaphylococcal penicillinFemaleFrancebusinessmedicine.drug
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