0000000000651327
AUTHOR
Celeste Dias
Frequency Domain Information Decomposition: Application to Plateau Waves of Intracranial Pressure
The sustainment and/or resurgence of Plateau Waves (PWs) reveals a borderline cerebral situation of the pressure-volume relationship and is related to increased mortality. The intense systemic stress caused by PWs can be evidenced by the study of Heart Rate Variability (HRV), which is an indicator of the activity of the autonomic nervous system, namely the sympathetic and parasympathetic imbalance. In this work, heart and brain crosstalk interactions will be analyzed using a spectral decomposition of multivariate information measures, which provides frequency-specific quantification of the information shared between a target and two source time series. The spectral measures of information h…
The impact of frailty on ICU and 30-day mortality and the level of care in very elderly patients (≥ 80 years)
Purpose: Very old critical ill patients are a rapid expanding group in the ICU. Indications for admission, triage criteria and level of care are frequently discussed for such patients. However, most relevant outcome studies in this group frequently find an increased mortality and a reduced quality of life in survivors. The main objective was to study the impact of frailty compared with other variables with regards to short-term outcome in the very old ICU population. Methods: A transnational prospective cohort study from October 2016 to May 2017 with 30 days follow-up was set up by the European Society of Intensive Care Medicine. In total 311 ICUs from 21 European countries participated. Th…