Exercise redox biology from health to performance

In order to support the energy demand during physical exercise, temporary acute responses occur in our organism to meet the homeostatic challenge imposed by the working muscles. As a result of the accumulation of exercise bouts the organism adapts. Exercise adaptations refer to the long-term changes that occur in our body as a consequence of training. The molecular bases of skeletal muscle adaptations to exercise such as mitochondrial biogenesis, hypertrophy, angiogenesis, and cytoprotection, are mediated by signaling events regulating transcriptional and translational processes and the activity of proteins involved in the maintenance of homeostasi.