0000000000652922
AUTHOR
A. Mancini
showing 3 related works from this author
EPATOBLASTOMI (EPB): UN SUCCESSO DELLA RIUCERCA CLINICA
1994
Dalla revisione della casistica del gruppo di Studio Italiano sui Tumori epatici del Bambino (GSTEB), risulta un miglioramento dell'Outcome di questi pazienti. Gli Autori presentano i risultati dello Studio.
Tratamiento del osteosarcoma localizado de las extremidades
1995
En la década de los setenta, la introducción de la quimioterapia preoperatoria en el tratamiento del osteosarcoma proporcionó mejoras dramáticas en los resultados obtenidos a largo plazo, en cuanto a la supervivencia libre de enfermedad y los procedimientos de salvación de miembros. En el presente trabajo se describe la experiencia acumulada en el Instituto Rizzoli, con la aplicación de varios protocolos activados sucesivamente. Igualmente, se describen los distintos factores pronósticos, la necrosis inducida por quimioterapia, dosis/intensidad y niveles séricos de metotrexato. In the seventies, the introduction of preoperative chemotherapy in the treatment of osteosarcoma dramatically impr…
Multiple hormonal and metabolic deficiency syndrome in chronic heart failure: rationale, design, and demographic characteristics of the T.O.S.CA. Reg…
2018
Recent evidence supports the concept that progression of chronic heart failure (CHF) depends upon an imbalance of catabolic forces over the anabolic drive. In this regard, multiple hormonal deficiency syndrome (MHDS) significantly has impacts upon CHF progression, and is associated with a worse clinical status and increased mortality. The T.O.S.CA. (Trattamento Ormonale nello Scompenso CArdiaco; Hormone Therapy in Heart Failure) Registry (clinicaltrial.gov = NCT02335801) tests the hypothesis that anabolic deficiencies reduce survival in a large population of mild-to-moderate CHF patients. The T.O.S.CA. Registry is a prospective multicenter observational study coordinated by “Federico II” Un…