0000000000657348

AUTHOR

Antje Eimermacher

showing 2 related works from this author

Clopidogrel and aspirin in the prevention of thromboembolic complications after mechanical aortic valve replacement (CAPTA)

2003

Axel Schlitt*, Ralf S. von Bardeleben, Anne Ehrlich, Antje Eimermacher, Dirk Peetz, Manfred Dahm, Hans J. Rupprecht Department of Medicine II, Johannes Gutenberg-University Mainz, Langenbeckstr. 1, 55131 Mainz, Germany Coordination Center for Clinical Studies, Johannes Gutenberg-University Mainz, Mainz, Germany Clinic for Clinical Chemistry and Laboratory Medicine, Johannes Gutenberg-University Mainz, Mainz, Germany Department of Cardiothoracic and Vascular Surgery, Johannes Gutenberg-University Mainz, Mainz, Germany

AdultMalemedicine.medical_specialtyTiclopidineTreatment outcomeAdministration OralHemorrhagePilot ProjectsValvula aorticaProstaglandin-Endoperoxide SynthaseThromboembolismmedicineHumansOral anticoagulationAgedAspirinAspirinbusiness.industryHematologyMiddle AgedClopidogrelClopidogrelSurgeryTreatment OutcomeAortic ValveHeart Valve ProsthesisAortic valve surgeryPhenprocoumonDrug Therapy CombinationFemalebusinessVenous diseasemedicine.drugThrombosis Research
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COX-2 expression in the guinea pig cochlea is partly altered by moderate sound exposure.

2006

The cyclooxygenase-2 isoform (COX-2) was found recently to be constitutively expressed in the guinea pig inner ear. To gain knowledge about its role in sound perception, alterations in the COX-2 level of moderate noise-stimulated cochleae were determined. Staining intensities were quantified in different regions using an immunohistochemical staining procedure and computer-assisted system. After 70 dB and 90 dB noise exposure for 1 h at 8000 Hz, COX-2 downregulation was observed in the organ of Corti, which was most prominent in Deiters' cells near Hensen cells and outer hair cells. In pillar cells, COX-2 levels were only slightly reduced after 70 dB but strongly diminished after 90 dB expos…

NeuronsGeneral NeuroscienceGuinea PigsGene ExpressionStimulationDose-Response Relationship RadiationSound perceptionAnatomyBiologyImmunohistochemistryCell biologyCochleaSound exposuremedicine.anatomical_structureAcoustic StimulationOrgan of CortiCyclooxygenase 2Spiral ligamentotorhinolaryngologic diseasesmedicineAnimalsInner earsense organsSpiral ganglionCochleaNeuroscience letters
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