0000000000661032

AUTHOR

Ewa Barg

showing 2 related works from this author

1H NMR-based metabolomics studies of urine reveal differences between type 1 diabetic patients with high and low HbAc1 values

2012

Abstract The aim of this study was to investigate relation between level of HbAc1 and concentration of metabolites in urine of T1D patients. To test this hypothesis the 1 H NMR (proton nuclear magnetic resonance) target analysis of crucial urine metabolites combined with chemometric approach were applied. Urine samples were collected from 30 children and teenagers aged 4–19 with T1D and 12 healthy children, aged 9, as control group. Patients were divided into two groups according to their level of glycated hemoglobin (HbA1c): below (L-T1D) and above 6.5% (H-T1D). The multivariate data analysis (OPLS-DA) was used to explore data and generate the models for selected groups of patients. Two ta…

MaleMagnetic Resonance SpectroscopyAdolescentendocrine system diseasesMetaboliteClinical BiochemistryPharmaceutical ScienceTarget analysisUrineAnalytical ChemistryYoung Adultchemistry.chemical_compoundMetabolomicsValineDrug DiscoveryHumansMetabolomicsAmino AcidsChildSpectroscopyGlycated HemoglobinAlanineChromatographynutritional and metabolic diseasesDiabetes Mellitus Type 1GlucosechemistryBiochemistryChild PreschoolProton NMRFemaleGlycated hemoglobinJournal of Pharmaceutical and Biomedical Analysis
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Analysis and comparison of autologous platelet-rich plasma preparation systems used in the treatment of enthesopathies: A preliminary study

2021

Background Autologous platelet-rich plasma (PRP) injection is an alternative but widely accepted method for the treatment of degenerative changes in tendon attachments known as enthesopathies. The PRP is considered a safe source for high concentrations of the growth factors involved in the healing process. Despite initial promising outcomes, many recent studies report conflicting results for this treatment. This may be due to differences in the concentrations of platelets and growth factors in PRPs obtained using different methods. Objectives The aim of this study was to compare PRP preparation systems in terms of morphotic components and selected growth factors to find the most appropriate…

Blood PlateletsMaleVascular Endothelial Growth Factor APlatelet-derived growth factormedicine.medical_treatmentPopulationMedicine (miscellaneous)EnthesopathyGeneral Biochemistry Genetics and Molecular Biologyplatelet-derived growth factorTransforming Growth Factor beta1AndrologyLeukocyte Countchemistry.chemical_compoundEpidermal growth factorgrowth factorsInternal MedicinemedicineHumansPharmacology (medical)PlateleteducationGenetics (clinical)Whole bloodeducation.field_of_studyEpidermal Growth FactorPlatelet-Rich Plasmabusiness.industryGrowth factorVascular endothelial growth factorchemistryPlatelet-rich plasmaReviews and References (medical)businessAdvances in Clinical and Experimental Medicine
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