0000000000668157

AUTHOR

L. Mancini

showing 8 related works from this author

Flux and color variations of the quadruply imaged quasar HE 0435-1223

2011

aims: We present VRi photometric observations of the quadruply imaged quasar HE 0435-1223, carried out with the Danish 1.54m telescope at the La Silla Observatory. Our aim was to monitor and study the magnitudes and colors of each lensed component as a function of time. methods: We monitored the object during two seasons (2008 and 2009) in the VRi spectral bands, and reduced the data with two independent techniques: difference imaging and PSF (Point Spread Function) fitting.results: Between these two seasons, our results show an evident decrease in flux by ~0.2-0.4 magnitudes of the four lensed components in the three filters. We also found a significant increase (~0.05-0.015) in their V-R …

Point spread functionCosmology and Nongalactic Astrophysics (astro-ph.CO)FluxFOS: Physical sciencesAstrophysicsAstrophysics::Cosmology and Extragalactic AstrophysicsGravitational microlensing01 natural scienceslaw.inventionTelescopeSettore FIS/05 - Astronomia e AstrofisicaObservatorylaw0103 physical sciencesAstrophysics::Solar and Stellar Astrophysics010303 astronomy & astrophysicsgeneral – gravitational lensing; weak – techniques: photometric [quasars]Astrophysics::Galaxy AstrophysicsPhysics010308 nuclear & particles physicsphotometric [Techniques]Astrophysics::Instrumentation and Methods for AstrophysicsAstronomy and AstrophysicsQuasargeneral [Quasars]Spectral bandsSpace and Planetary Scienceastro-ph.COAstrophysics::Earth and Planetary Astrophysicsweak [Gravitational lensing]Astrophysics - Cosmology and Nongalactic Astrophysics
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Pruritus characteristics in a large Italian cohort of psoriatic patients

2019

Background: Psoriasis (Ps) is a chronic systemic autoimmune disease associated with pruritus in 64–98% of patients. However, few modestly sized studies assess factors associated with psoriatic pruritus. Objective: To investigate factors associated with Ps pruritus intensity. Methods: Psoriasis patients 18 years or older seen in one of 155 centres in Italy between September 2005 and 2009 were identified from the Italian PsoCare registry. Patients without cutaneous psoriasis and those with missed information on pruritus were excluded. Results: We identified 10 802 patients, with a mean age 48.8 ± 14.3 years. Mild itch was present in 33.2% of patients, moderate in 34.4%, severe in 18.7% and ve…

MaleCross-sectional studySeverity of Illness IndexCohort Studies030207 dermatology & venereal diseases0302 clinical medicineRisk Factorseducation; itch; pruritus; psoriasis; pustular psoriasis; treatment; Adolescent; Adult; Cohort Studies; Cross-Sectional Studies; Educational Status; Facial Dermatoses; Female; Foot Dermatoses; Genitalia; Hand Dermatoses; Humans; Italy; Male; Middle Aged; Pruritus; Psoriasis; Registries; Risk Factors; Severity of Illness Index; Sex Factors; Young AdultEpidemiologyitchRegistriesYoung adultskin and connective tissue diseaseseducationtreatmentMiddle AgedSettore MED/33 - MALATTIE APPARATO LOCOMOTOREInfectious Diseasespustular psoriasisItaly030220 oncology & carcinogenesisCohortEducational StatusPRURITIS EPIDEMIOLOGYFemaleSettore MED/35 - MALATTIE CUTANEE E VENEREECohort studyAdultmedicine.medical_specialtyAdolescentPSORIASDermatologyHand DermatosesArticle03 medical and health sciencesYoung AdultPharmacotherapySex FactorsSettore MED/35PsoriasisSeverity of illnessmedicineHumansPsoriasisGenitaliaFoot Dermatosesbusiness.industryPruritusmedicine.diseaseDermatologyPruritusItch sensationCross-Sectional StudiesbusinessFacial Dermatoses
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Efficacy of switching between tumor necrosis factor-alfa inhibitors in psoriasis: results from the Italian Psocare registry

2014

Background: Some studies have shown that switching patients from one tumor necrosis factor (TNF)-alfa inhibitor to another may be beneficial when they have an inadequate response or an adverse event. Objective: We sought to assess the variables predicting the efficacy of the second TNF-alfa inhibitor in patients discontinuing the first TNF-alfa inhibitor. Methods: Data from all 5423 consecutive patients starting TNF-alfa inhibitor therapy for psoriasis between September 2005 and September 2010 who were included in the Italian Psocare registry were analyzed. Results: In 105 patients who switched to a second TNF-alfa inhibitor who had complete follow-up data, 75% improvement in the Psoriasis …

Maleprimary inefficacy75% improvement in the Psoriasis Area Severity Index score; PASI; PASI 75; Psoriasis Area Severity Index; TNF; biologics; efficacy; primary inefficacy; psoriasis; secondary loss of efficacy; switching; tumor necrosis factor; tumor necrosis factor-alfa inhibitors; Adult; Analysis of Variance; Antibodies Monoclonal; Antibodies Monoclonal Humanized; Cohort Studies; Confidence Intervals; Dose-Response Relationship Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Immunoglobulin G; Italy; Male; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Proportional Hazards Models; Psoriasis; Receptors Tumor Necrosis Factor; Registries; Retrospective Studies; Risk Assessment; Severity of Illness Index; Treatment Outcome; Tumor Necrosis Factor-alpha; Young AdultSWITHCESefficacyTNFpsoriasis; psoriasis arthritis; pharmachological treatmentPASI 75Severity of Illness IndexReceptors Tumor Necrosis FactorEtanerceptCohort StudiesMonoclonalReceptorsSettore MED/35 - Malattie Cutanee E VenereeRegistriesHumanizedtumor necrosis factor-alfa inhibitors.switchingHazard ratioAntibodies MonoclonalMiddle AgedTreatment OutcomeItalyPredictive value of tests75% improvement in the Psoriasis Area Severity Index scoreFemaleDrugPsoriasis Area Severity IndexbiologicTNF-alphaAdultmedicine.medical_specialtytumor necrosis factorDermatology75% improvement in the Psoriasis Area Severity Index score; PASI; PASI 75; Psoriasis Area Severity Index; TNF; biologics; efficacy; primary inefficacy; psoriasis; secondary loss of efficacy; switching; tumor necrosis factor; tumor necrosis factor-alfa inhibitorsAntibodies Monoclonal Humanizedsecondary loss of efficacyRisk AssessmentAntibodiestumor necrosis factor-alfa inhibitorsDrug Administration ScheduleDose-Response RelationshipYoung AdultSettore MED/35Predictive Value of TestsInternal medicinePsoriasisSeverity of illnessmedicineConfidence IntervalsHumansPsoriasisbiologicsAdverse effectPsoriasis; TNF-alphaProportional Hazards ModelsRetrospective Studiespsoriasibiologics; efficacy; primary inefficacy; psoriasis; secondary loss of efficacy; switching; tumor necrosis factor-alfa inhibitors; Adalimumab; Adult; Analysis of Variance; Antibodies Monoclonal; Antibodies Monoclonal Humanized; Cohort Studies; Confidence Intervals; Dose-Response Relationship Drug; Drug Administration Schedule; Etanercept; Female; Follow-Up Studies; Humans; Immunoglobulin G; Infliximab; Italy; Male; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Proportional Hazards Models; Psoriasis; Receptors Tumor Necrosis Factor; Registries; Retrospective Studies; Risk Assessment; Severity of Illness Index; Treatment Outcome; Tumor Necrosis Factor-alpha; Young Adult; 2708Analysis of Variancepharmachological treatmentDose-Response Relationship DrugProportional hazards modelbusiness.industrytumor necrosis factor-alfa inhibitorTumor Necrosis Factor-alphaPASIAdalimumabRetrospective cohort studypsoriasis arthritismedicine.diseaseConfidence intervalInfliximabSurgeryImmunoglobulin GMultivariate AnalysisANTI-TNFAbusiness2708Follow-Up Studies
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A giant planet beyond the snow line in microlensing event OGLE-2011-BLG-0251

2013

We present the analysis of the gravitational microlensing event OGLE-2011-BLG-0251. This anomalous event was observed by several survey and follow-up collaborations conducting microlensing observations towards the Galactic Bulge. Based on detailed modelling of the observed light curve, we find that the lens is composed of two masses with a mass ratio q=1.9 x 10^-3. Thanks to our detection of higher-order effects on the light curve due to the Earth's orbital motion and the finite size of source, we are able to measure the mass and distance to the lens unambiguously. We find that the lens is made up of a planet of mass 0.53 +- 0.21,M_Jup orbiting an M dwarf host star with a mass of 0.26 +- 0.…

planets and satellites: detection010504 meteorology & atmospheric sciencesSatellitesbulge [Galaxy]FOS: Physical sciencesAstrophysicsAstrophysics::Cosmology and Extragalactic AstrophysicsDiscoveryGravitational microlensing01 natural sciencesGalaxy: bulgeEinstein radiusLensgravitational lensing: weakSettore FIS/05 - Astronomia e AstrofisicaPlanetSnow0103 physical sciencesgravitational lensing; weak; planets and satellites; detection; planetary systems; Galaxy; bulgegravitational lensing: weak; planets and satellites: detection; planetary systems; Galaxy: bulgeBinaryQB Astronomy010303 astronomy & astrophysicsplanetary systemsAstrophysics::Galaxy Astrophysics0105 earth and related environmental sciencesQBPhysicsEarth and Planetary Astrophysics (astro-ph.EP)Giant planetSystemsSearchAstronomy and AstrophysicsRadiusFrequencyPlanetary systemMass ratioMassLight curveStarsAlgorithmdetection [Planets and satellites]Planetary systemsSpace and Planetary ScienceDwarfAstrophysics::Earth and Planetary Astrophysicsweak [Gravitational lensing]Astrophysics - Earth and Planetary AstrophysicsAstronomy and Astrophysics
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Inferring statistics of planet populations by means of automated microlensing searches

2008

(abridged) The study of other worlds is key to understanding our own, and not only provides clues to the origin of our civilization, but also looks into its future. Rather than in identifying nearby systems and learning about their individual properties, the main value of the technique of gravitational microlensing is in obtaining the statistics of planetary populations within the Milky Way and beyond. Only the complementarity of different techniques currently employed promises to yield a complete picture of planet formation that has sufficient predictive power to let us understand how habitable worlds like ours evolve, and how abundant such systems are in the Universe. A cooperative three-…

Astrophysics (astro-ph)FOS: Physical sciencesAstrophysics::Cosmology and Extragalactic AstrophysicsAstrophysics::Earth and Planetary AstrophysicsAstrophysicsAstrophysics::Galaxy Astrophysics
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Characterizing Lenses and Lensed Stars of High-magnification Single-lens Gravitational Microlensing Events with Lenses Passing over Source Stars

2012

We present the analysis of the light curves of 9 high-magnification single-lens gravitational microlensing events with lenses passing over source stars, including OGLE-2004-BLG-254, MOA-2007-BLG-176, MOA-2007-BLG-233/OGLE-2007-BLG-302, MOA-2009-BLG-174, MOA-2010-BLG-436, MOA-2011-BLG-093, MOA-2011-BLG-274, OGLE-2011-BLG-0990/MOA-2011-BLG-300, and OGLE-2011-BLG-1101/MOA-2011-BLG-325. For all events, we measure the linear limb-darkening coefficients of the surface brightness profile of source stars by measuring the deviation of the light curves near the peak affected by the finite-source effect. For 7 events, we measure the Einstein radii and the lens-source relative proper motions. Among the…

Physics010308 nuclear & particles physicsBrown dwarfFOS: Physical sciencesAstronomy and Astrophysicsgravitational lensing: microAstrophysicsMass ratioLight curveGravitational microlensing01 natural sciencesGalaxy: bulgeGalaxy: bulge gravitational lensing: microEinstein radiuslaw.inventionLens (optics)StarsAstrophysics - Solar and Stellar AstrophysicsSettore FIS/05 - Astronomia e AstrofisicaSpace and Planetary Sciencelaw0103 physical sciencesSurface brightness010303 astronomy & astrophysicsSolar and Stellar Astrophysics (astro-ph.SR)
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KELT-9b radial velocity curve

2019

In the framework of the GAPS project, we observed the planet-hosting star KELT-9 (A-type star, vsini~110km/s) with the HARPS-N spectrograph at the Telescopio Nazionale Galileo. In this work we analyse the spectra and the extracted radial velocities, to constrain the physical parameters of the system and to detect the planetary atmosphere of KELT-9b. We extracted from the high-resolution optical spectra the mean stellar line profiles with an analysis based on the Least Square Deconvolution technique. Then, we computed the stellar radial velocities with a method optimized for fast rotators, by fitting the mean stellar line profile with a purely rotational profile instead of using a Gaussian f…

observational astronomyRadial velocityAstrophysics and AstronomyExoplanet AstronomyStellar AstronomyExoplanetsPhysicsAstrophysics::Solar and Stellar AstrophysicsAstrophysics::Earth and Planetary AstrophysicsMultiple starsNatural SciencesSpectroscopy
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Microlensing Discovery of a Population of Very Tight, Very Low Mass Binary Brown Dwarfs

2013

Although many models have been proposed, the physical mechanisms responsible for the formation of low-mass brown dwarfs (BDs) are poorly understood. The multiplicity properties and minimum mass of the BD mass function provide critical empirical diagnostics of these mechanisms. We present the discovery via gravitational microlensing of two very low mass, very tight binary systems. These binaries have directly and precisely measured total system masses of 0.025 M [SUB]⊙[/SUB] and 0.034 M [SUB]⊙[/SUB], and projected separations of 0.31 AU and 0.19 AU, making them the lowest-mass and tightest field BD binaries known. The discovery of a population of such binaries indicates that BD binaries can …

Aérospatiale astronomie & astrophysiquebinaries: generalPhysical chemical mathematical & earth SciencesPhysique chimie mathématiques & sciences de la terreSpace science astronomy & astrophysicsgravitational lensing: micro
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