0000000000669969

AUTHOR

R.s. De Molon

showing 3 related works from this author

sj-docx-1-jdr-10.1177_00220345211027811 – Supplemental material for Phytocystatin CsinCPI-2 Reduces Osteoclastogenesis and Alveolar Bone Loss

2021

Supplemental material, sj-docx-1-jdr-10.1177_00220345211027811 for Phytocystatin CsinCPI-2 Reduces Osteoclastogenesis and Alveolar Bone Loss by N. Da Ponte Leguizamón, R.S. de Molon, G. Coletto-Nunes, A.V.B. Nogueira, S.V. Rocha, D.M. Neo-Justino, A. Soares-Costa, P.S. Cerri, U.H. Lerner, P.P.C. Souza and J.A. Cirelli in Journal of Dental Research

110599 Dentistry not elsewhere classifiedFOS: Materials engineeringFOS: Clinical medicine91299 Materials Engineering not elsewhere classified
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Phytocystatin CsinCPI-2 Reduces Osteoclastogenesis and Alveolar Bone Loss

2021

Made available in DSpace on 2022-04-28T19:42:37Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-02-01 Periodontal disease (PD) is a polymicrobial chronic inflammatory condition of the supporting tissues around the teeth, leading to the destruction of surrounding connective tissue. During the progression of PD, osteoclasts play a crucial role in the resorption of alveolar bone that eventually leads to the loss of teeth if the PD is left untreated. Therefore, the development of antiresorptive therapies targeting bone-resorbing cells will significantly benefit the treatment of PD. Here, we demonstrate the inhibitory effect of CsinCPI-2, a novel cysteine peptidase inhibitor from the oran…

0301 basic medicineAlveolar Bone LossConnective tissueOsteoclastsInflammationBone resorption03 medical and health sciencesMice0302 clinical medicineOsteoclastOsteogenesismedicineAnimalsProtease InhibitorsBone ResorptionPeriodontitisGeneral DentistryperiodontitisDental alveolusPeriodontitisChemistryRANK LigandCell Differentiation030206 dentistrymedicine.diseaseCystatinsResorption030104 developmental biologymedicine.anatomical_structureosteoclastsinflammationCancer researchBone marrowmedicine.symptombone resorptionperiodontal diseasescystatins
researchProduct

sj-docx-1-jdr-10.1177_00220345211027811 – Supplemental material for Phytocystatin CsinCPI-2 Reduces Osteoclastogenesis and Alveolar Bone Loss

2021

Supplemental material, sj-docx-1-jdr-10.1177_00220345211027811 for Phytocystatin CsinCPI-2 Reduces Osteoclastogenesis and Alveolar Bone Loss by N. Da Ponte Leguizamón, R.S. de Molon, G. Coletto-Nunes, A.V.B. Nogueira, S.V. Rocha, D.M. Neo-Justino, A. Soares-Costa, P.S. Cerri, U.H. Lerner, P.P.C. Souza and J.A. Cirelli in Journal of Dental Research

110599 Dentistry not elsewhere classifiedFOS: Materials engineeringFOS: Clinical medicine91299 Materials Engineering not elsewhere classified
researchProduct