0000000000670654
AUTHOR
M Calabrese
showing 5 related works from this author
Addition of either pioglitazone or a sulfonylurea in type 2 diabetic patients inadequately controlled with metformin alone: impact on cardiovascular …
2012
Abstract Background and aims Metformin is the first-line therapy in type 2 diabetes. In patients inadequately controlled with metformin, the addition of a sulfonylurea or pioglitazone are equally plausible options to improve glycemic control. However, these drugs have profound differences in their mechanism of action, side effects, and impact on cardiovascular risk factors. A formal comparison of these two therapies in terms of cardiovascular morbidity and mortality is lacking. The TOSCA.IT study was designed to explore the effects of adding pioglitazone or a sulfonylurea on cardiovascular events in type 2 diabetic patients inadequately controlled with metformin. Methods Multicentre, random…
La trasmissione del trauma:il caso dei sopravvissuti della Shoah
2011
The aim of this study is to analize how individual subjectivity is influenced and in part determined by psychic life of past generation and by belonging community or cultural groups. To particularly, we tried to unterstand how massive and non-sense traumas, like Shoah, may continue to act on following generations deeply marking them: descendants of survivors of this tragic event had, in fact, the task of finding a solutions to unresolved and unelaborated traumas of their parents and the Jewish people in general, so the second generation became the recipient of emotive real life that have structured the parent's experiences. Deep interviews have been conducted with some ex-deported and some …
I beni relazionali nei gruppi di formazione universitaria: un contributo di ricerca
2009
The aim of the study is to identify relational goods in the transcriptions produced by sound recording of a median group experience at University of Palermo. In particular, the present work proposes to analyze the most representative qualities of this phenomenon and summarized them in the following indicators: 1) emergent fact; 2) recognition; 3) solidarity. Our theoretical hypothesis is based on the fundamental group analytic epistemological assumption that defines relation as the beginning of the development of human psyche and considers the Group a primary matrix in which originate subjectivity and human relationship (Lo Verso, 1994; Mitchell, 2000). Therefore, the group becomes the elec…
Effects on the incidence of cardiovascular events of the addition of pioglitazone versus sulfonylureas in patients with type 2 diabetes inadequately …
2017
Background The best treatment option for patients with type 2 diabetes in whom treatment with metformin alone fails to achieve adequate glycaemic control is debated. We aimed to compare the long-term effects of pioglitazone versus sulfonylureas, given in addition to metformin, on cardiovascular events in patients with type 2 diabetes. Methods TOSCA.IT was a multicentre, randomised, pragmatic clinical trial, in which patients aged 50â75 years with type 2 diabetes inadequately controlled with metformin monotherapy (2â3 g per day) were recruited from 57 diabetes clinics in Italy. Patients were randomly assigned (1:1), by permuted blocks randomisation (block size 10), stratified by site and…
Potassium deficiency and drought stress in grapevine cultivars
2014
Potassium availability affects drought responses in plants through several metabolic roles, among which stomatal regulation, cell growth and xylem hydraulics. Vitis vinifera L. is a highly valuable crop and several genotypes have been selected during its millennial cultivation. Varieties show differences in their adaptability to stress conditions, making them more or less suitable to certain climatic and edaphic conditions. The varieties cultivated in Sicily are characterized by high variability. We investigated the response of two Sicilian cultivars (Nero d'Avola and Catarratto) to potassium deficiency and drought stress. Two-year-old grafted plants were grown in agriperlite, with or witho…