0000000000670740

AUTHOR

D. Martinelli

showing 3 related works from this author

COVID-19: opinions and behavior of Italian general population during the first epidemic phase

2022

Background and aim: On January 9, 2020, the World Health Organization (WHO) declared that Chinese health authorities had identified a new coronavirus strain never before isolated in humans, the 2019-nCoV later redefined SARS-CoV-2, that still today represent a public health problem. The present survey started on 10 February 2020 with the aim of a) assessing the risk perception in healthcare workers and young students, following the evolution of attitudes, perception and knowledge over time, b) provide useful information to the general population during survey. Results: A study sample consisting of 4116 Italian in-dividuals of both sexes was enrolled. High levels of risk perception, low perc…

risk perception.MaleknowledgeSARS-CoV-2attitude; COVID-19; knowledge; perception; population; risk perceptionpopulationCOVID-19perceptionattitude COVID-19 knowledge perception population risk perceptionAttituderisk perceptionCOVID-19; risk perception; knowledge; attitude; perception; populationattitudeHumansFemalePublic HealthEpidemicsHuman
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Effect of RNS60 in amyotrophic lateral sclerosis: a phase II multicentre, randomized, double-blind, placebo-controlled trial

2022

Background and purpose: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with limited treatment options. RNS60 is an immunomodulatory and neuroprotective investigational product that has shown efficacy in animal models of ALS and other neurodegenerative diseases. Its administration has been safe and well tolerated in ALS subjects in previous early phase trials. Methods: This was a phase II, multicentre, randomized, double-blind, placebo-controlled, parallel-group trial. Participants diagnosed with definite, probable or probable laboratory-supported ALS were assigned to receive RNS60 or placebo administered for 24 weeks intravenously (375 ml) once a week and via nebul…

treatmentAmyotrophic Lateral Sclerosisplacebo-controlledNeurodegenerative DiseasesALS; clinical trial; placebo-controlled; randomized; treatmentclinical trialTreatment OutcomeNeurologyDouble-Blind MethodrandomizedQuality of LifeHumansSettore MED/26 - NeurologiaNeurology (clinical)ALSBiomarkers
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Antimeningococcal and antipneumococcal vaccination determinants: A European systematic literature review

2015

Background. ESCULAPIO is a multicenter project, funded by the Italian Centre for Disease Prevention and Control, aimed at implementing communication strategies to improve vaccination knowledge and attitudes among different target populations. Objective. The objective of the Sicilian research unit was, in the first phase, to identify, through systematic literature revision, which vaccination determinants play a role in the uptake of recommended vaccines included in the Italian Vaccination Plan. Design. A systematic literature review was carried out on studies describing the determinants underlying pneumococcal and meningococcal vaccination uptake. The analysis was limited to papers published…

AdultMaleParentsHealth Knowledge Attitudes PracticeAdolescentMeningococcal VaccinesSettore MED/42 - Igiene Generale E ApplicataVulnerable PopulationsHealth Services AccessibilityPneumococcal InfectionsPneumococcal VaccinesVaccination RefusalMeningococcal vaccination; Pneumococcal vaccination; Systematic literature review; Epidemiology; Public Health Environmental and Occupational HealthHumanssystematic literature review meningococcal vaccination pneumococcal vaccinationChildAgedAged 80 and overVaccinationAge FactorsInfantEuropeMeningococcal InfectionsSocioeconomic FactorsChild PreschoolCosts and Cost AnalysisFemale
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