0000000000673726

AUTHOR

Oliver Pogarell

showing 2 related works from this author

Cannabiskonsum zum Freizeitgebrauch

2019

Zur gezielten Aufnahme, Verarbeitung und Speicherung der komplexen sensorischen Informationen unserer Umwelt benotigen wir kognitive Fahigkeiten. Unter „Kognition” versteht man dabei eine Vielzahl bewusster sowie unbewusster neuronaler Prozesse des Gehirns, die bei der Verarbeitung externer und interner Informationen ablaufen.

researchProduct

Possible association between OPRM1 genetic variance at the 118 locus and alcohol dependence in a large treatment sample: relationship to alcohol depe…

2012

Background Several lines of evidence from previous research indicate that opioid receptors play an important role in ethanol reinforcement and alcohol dependence (AD) risk. Conflicting results were reported on the role of the mu-opioid receptor (OPRM1) polymorphism A118G (Asn40Asp, rs1799971) in the development of alcoholism. Methods We investigated a total number of 1,845 alcohol-dependent subjects recruited from inpatient facilities in Germany and 1,863 controls for the mu-opioid receptor (OPRM1) polymorphism using chi-square statistics. Results An association between the OPRM variant and AD was detected (p = 0.022), in recessive (AA vs. GA/GG) and co-dominant (AA vs. GA) models of inheri…

OncologyAdultMalemedicine.medical_specialtymedicine.drug_classReceptors Opioid muMedicine (miscellaneous)Locus (genetics)AlcoholToxicologychemistry.chemical_compoundOpioid receptorInternal medicineGenetic variationmedicineHumansReceptorGenetic Association StudiesGeneticsAlcohol dependenceGenetic VariationMiddle AgedPsychiatry and Mental healthAlcoholismTreatment OutcomechemistryOpioidGenetic LociPopulation SurveillanceMultiple comparisons problemFemalePsychologymedicine.drugAlcoholism, clinical and experimental research
researchProduct