0000000000680657

AUTHOR

Gregor Buch

showing 3 related works from this author

Abstract 13812: Pulmonary Function Predicts Cardiac Function, Structure & Clinical Outcome in Chronic Heart Failure: Results From the Myovasc Stu…

2020

Introduction: A growing body of evidence suggests a relevance of pulmonary function in the pathophysiology of heart failure (HF). Comprehensive data on the role of forced expiratory volume in 1 second (FEV1) in the development & progression of HF is limited. Hypothesis: Given this background, we hypothesized, that (FEV1) is associated with deteriorated left ventricular (LV) functional as well as structural status, & predicts specific clinical outcome in HF. Methods: Data from the MyoVasc Study (n=3,289) were analysed. Comprehensive clinical phenotyping including body plethysmography for the evaluation of FEV1 & standardized echocardiography were performed during a five-hour inv…

Cardiac function curvemedicine.medical_specialtybusiness.industrymedicine.diseaseOutcome (game theory)PathophysiologyPulmonary function testingPhysiology (medical)Internal medicineHeart failureEpidemiologyCardiologymedicineCardiology and Cardiovascular MedicinebusinessCirculation
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FEV1 Predicts Cardiac Status and Outcome in Chronic Heart Failure

2022

Background COPD is an established predictor of clinical outcome in patients with chronic heart failure (HF). However, little evidence is available about the predictive value of FEV1 in chronic HF. Research Question Is pulmonary function related to the progression of chronic HF? Study Design and Methods The MyoVasc study ( ClinicalTrials.gov Identifier: NCT04064450) is a prospective cohort study of HF. Information on pulmonary and cardiac functional and structural status was obtained by body plethysmography and echocardiography. The primary study end point was worsening of HF. Results Overall 2,998 participants (age range, 35-84 years) with available FEV1 data were eligible for analysis. Lin…

Pulmonary and Respiratory MedicineCardiac function curvemedicine.medical_specialtyCOPDEjection fractionbusiness.industryDiastoleCritical Care and Intensive Care Medicinemedicine.diseasePulmonary function testingInternal medicineHeart failureCardiologyMedicineCardiology and Cardiovascular MedicinebusinessHeart failure with preserved ejection fractionProspective cohort studyChest
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Chronic venous insufficiency, cardiovascular disease, and mortality: a population study

2021

Abstract Aims  Evidence regarding the health burden of chronic venous insufficiency (CVI), its clinical determinants, and impact on outcome is scarce. Methods and results  Systematic phenotyping of CVI according to established CEAP (Clinical-Etiologic-Anatomic-Pathophysiologic) classification was performed in 12 423 participants (age range: 40–80 years) of the Gutenberg Health Study from April 2012 to April 2017. Prevalence was calculated age- and sex-specifically. Multivariable Poisson regression models were calculated to evaluate the relation of CVI with cardiovascular comorbidities. Survival analyses were carried out to assess the CVI-associated risk of death. Replication of findings was…

medicine.medical_specialtyChronic venous insufficiencyEpidemiologyPopulationMECHANISMSInternal medicineEpidemiologymedicineVARICOSE-VEINSeducationRISKeducation.field_of_studybusiness.industryHazard ratioWOMENChronic venous insufficiencyASSOCIATIONmedicine.diseaseCardiovascular diseaseAll-cause mortalityComorbidityPREGNANCYATHEROSCLEROSISCohortPopulation studySurgeryCardiology and Cardiovascular MedicinebusinessCohort studyEuropean Heart Journal
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