0000000000682310

AUTHOR

Katerina Kousoulaki

0000-0002-8021-5452

showing 3 related works from this author

Cytoprotective Effects of Fish Protein Hydrolysates against H2O2-Induced Oxidative Stress and Mycotoxins in Caco-2/TC7 Cells

2021

Many studies report the potent antioxidant capacity for fish protein hydrolysates, including radical scavenging activity and inhibition ability on lipid peroxidation (LPO). In this study, the in vitro cytotoxicity of protein hydrolysates from different salmon, mackerel, and herring side streams fractions was evaluated in the concentration range from 1 to 1:32 dilution, using cloned human colon adenocarcinoma cells TC7 (Caco-2/TC7) by MTT and PT assays. The protein hydrolysates’ antioxidant capacity and oxidative stress effects were evaluated by LPO and reactive oxygen species (ROS) generation, respectively. The antioxidant capacity for pure and bioavailable hydrolysate fraction was also eva…

0301 basic medicinePhysiologyClinical BiochemistryRM1-950medicine.disease_causeBiochemistryHydrolysateArticleLipid peroxidation03 medical and health scienceschemistry.chemical_compound0404 agricultural biotechnologymedicineoxidative stressFood scienceViability assayCytotoxicityMolecular Biologychemistry.chemical_classificationReactive oxygen species030109 nutrition & dieteticsToxin04 agricultural and veterinary sciencesCell Biology040401 food scienceBioavailabilitychemistrycytoprotective effectcytotoxicityTherapeutics. Pharmacologyfish hydrolysatesbioavailabilityOxidative stressAntioxidants
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Improved Extraction Efficiency of Antioxidant Bioactive Compounds from Tetraselmis chuii and Phaedoactylum tricornutum Using Pulsed Electric Fields

2020

Pulsed electric fields (PEF) is a promising technology that allows the selective extraction of high-added value compounds by electroporation. Thus, PEF provides numerous opportunities for the energy efficient isolation of valuable microalgal bioactive substances (i.e., pigments and polyphenols). The efficiency of PEF-assisted extraction combined with aqueous or dimethyl sulfoxide (DMSO) solvents in recovering pigments and polyphenols from microalgae Tetraselmis chuii (T. chuii) and Phaeodactylum tricornutum (P. tricornutum) was evaluated. Two PEF treatments were applied: (1 kV/cm/400 pulses, 3 kV/cm/45 pulses), with a specific energy input of 100 kJ/kg. The total antioxidant capacity (TAC) …

0106 biological sciencesChlorophyll bAntioxidantmedicine.medical_treatmentPharmaceutical ScienceTetraselmis chuii01 natural sciencesPhaeodactylum tricornutumArticleAntioxidantsAnalytical Chemistrylcsh:QD241-441chemistry.chemical_compound0404 agricultural biotechnologylcsh:Organic chemistryChlorophyta010608 biotechnologyDrug DiscoverymedicineMicroalgaePhaeodactylum tricornutum<i>Phaeodactylum tricornutum</i>Physical and Theoretical ChemistryTetraselmis<i>Tetraselmis chuii</i>Carotenoidchemistry.chemical_classificationDiatomsChromatographybiologyChemistryDimethyl sulfoxideOrganic ChemistryExtraction (chemistry)Polyphenols04 agricultural and veterinary sciencesbiology.organism_classification040401 food science6. Clean waterElectroporationpulsed electric fieldsChemistry (miscellaneous)PolyphenolextractionMolecular Medicineantioxidant bioactive compoundsMolecules
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Innovative Green Technologies of Intensification for Valorization of Seafood and Their By-Products

2019

The activities linked to the fishing sector generate substantial quantities of by-products, which are often discarded or used as low-value ingredients in animal feed. However, these marine by-products are a prominent potential good source of bioactive compounds, with important functional properties that can be isolated or up-concentrated, giving them an added value in higher end markets, as for instance nutraceuticals and cosmetics. This valorization of fish by-products has been boosted by the increasing awareness of consumers regarding the relationship between diet and health, demanding new fish products with enhanced nutritional and functional properties. To obtain fish by-product-derived…

030309 nutrition & dieteticsEmerging technologiesmedia_common.quotation_subjectPharmaceutical ScienceCosmeticsReviewCosmetics03 medical and health sciencesIngredient0404 agricultural biotechnologyNutraceuticalinnovative green technologieshigh-added value compoundsDrug DiscoveryFish ProductsAdded valueAnimalsHumansQuality (business)Ultrasonics14. Life underwaterPharmacology Toxicology and Pharmaceutics (miscellaneous)functional foodsmedia_common0303 health sciencesBiological Productsseafood by-productsSupercritical fluid extractionChromatography Supercritical FluidGreen Chemistry Technology04 agricultural and veterinary sciencesFish products040401 food scienceSeafoodDietary SupplementsBiochemical engineeringBusiness
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