0000000000682681

AUTHOR

Aurel Radulescu

0000-0002-6050-0176

showing 3 related works from this author

Hybrid Biopolymer and Lipid Nanoparticles with Improved Transfection Efficacy for mRNA

2020

Cells 9(9), 2034 (1-19) (2020). doi:10.3390/cells9092034

0301 basic medicine570small angle scatteringNanoparticlecationic lipid02 engineering and technologyengineering.materialTransfectionArticleCell LineFatty Acids Monounsaturated03 medical and health sciencesMiceBiopolymersddc:570AnimalsHumansRNA MessengerParticle Sizelcsh:QH301-705.5chemistry.chemical_classificationMice Inbred BALB Ccancer immunotherapySmall-angle X-ray scatteringHeparinOptical ImagingCationic polymerizationGeneral MedicinePolymerTransfection021001 nanoscience & nanotechnologyvaccinationSmall-angle neutron scatteringLipidslipid-polymer hybrid nanoparticlesQuaternary Ammonium Compounds030104 developmental biologychemistrylcsh:Biology (General)cationic polymerBiophysicsengineeringNanoparticlesRNAFemalePolymer blendBiopolymer0210 nano-technologyCovid-19
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Mesoscopic and Microscopic Investigation on Poly(vinyl alcohol) Hydrogels in the Presence of Sodium Decylsulfate

2007

The structure of poly(vinyl alcohol) (PVA) hydrogels formed as a result of freeze/thaw treatments of aqueous solutions of the polymer (11 wt % PVA) in the freshly prepared state is analyzed through the combined use of small (SANS) and ultrasmall (USANS) angle neutron scattering techniques. The structure of these hydrogels may be described in terms of polymer rich regions, with dimensions of the order of 1-2 microm, dispersed in a water rich phase, forming two bicontinuous phases. The PVA chains in the polymer rich phase form a network where the cross-linking points are mainly crystalline aggregates of PVA having average dimensions of approximately 45 A. The structural organization of freeze…

Vinyl alcoholMaterials scienceBiophysicsANGLE NEUTRON-SCATTERINGMicellePolyvinyl alcoholELECTRON-PARAMAGNETIC-RESONANCESurface-Active Agentschemistry.chemical_compoundDrug Delivery SystemsPulmonary surfactantTensile StrengthPhase (matter)Materials TestingPolymer chemistryMaterials ChemistryScattering RadiationPhysical and Theoretical ChemistryPolymerULTRA-SMALL-ANGLENeutronschemistry.chemical_classificationDRUG-DELIVERY SYSTEMSModels StatisticalAqueous solutionintegumentary systemChemistry PhysicalSANSElectron Spin Resonance SpectroscopyHydrogelsPolymerSurfaces Coatings and FilmsHydrogelchemistryPolyvinyl AlcoholSelf-healing hydrogelsStress MechanicalEPRSulfonic Acids
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Investigation of charge ratio variation in mRNA – DEAE-dextran polyplex delivery systems

2019

Biomaterials 192, 612 - 620 (2019). doi:10.1016/j.biomaterials.2018.10.020

570Static ElectricityBiophysicsBioengineering02 engineering and technologyGene deliveryBiomaterials03 medical and health scienceschemistry.chemical_compoundDrug Delivery SystemsX-Ray DiffractionDynamic light scatteringddc:570Scattering Small AngleHumansRNA MessengerParticle Size030304 developmental biology0303 health sciencesMessenger RNAHeparinSmall-angle X-ray scatteringDEAE-DextranBiological activityDendritic CellsTransfection021001 nanoscience & nanotechnologySmall-angle neutron scatteringDextranchemistryMechanics of MaterialsCeramics and CompositesBiophysics0210 nano-technology
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