0000000000685385

AUTHOR

Ana Angelova Volponi

showing 2 related works from this author

In-vitro regulation of odontogenic gene expression in human embryonic tooth cells and SHED cells

2012

The bud-to-cap stage transition during early tooth development is a time when the tooth-inducing potential becomes restricted to the mesenchyme. Several key genes, expressed in the mesenchyme at this stage, are an absolute requirement for the progression of tooth development. These include the transcription factors Msx1 and Pax9. The inductive potential of tooth mesenchyme cells is a key requisite for whole-tooth bioengineering and thus identification of cells that can retain this property following expansion in culture is an important as yet unresolved, goal. We show here that in-vitro culture of embryonic human tooth mesenchyme cells and SHED cells express low levels of PAX9 and MSX1 and …

MesodermCell signalingHistologyMesenchymeSHEDPAX9MSX1tissue engineering cell signallingBone Morphogenetic Protein 4BiologyCell LinePathology and Forensic MedicineMesodermstomatognathic systemmedicineHumansChildMSX1 Transcription FactorRegulation of gene expressionMesenchymal stem cellGene Expression Regulation DevelopmentalCell BiologyEmbryonic stem cellCell biologystomatognathic diseasesmedicine.anatomical_structureBone morphogenetic protein 4Cell cultureImmunologyOdontogenesisPAX9 Transcription FactorToothSignal TransductionCell and Tissue Research
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Regulation of odontogenic gene expression in dental stem cells

2010

Italian Journal of Anatomy and Embryology, Vol 115, No 1/2 (Supplement) 2010

odontogenic genes dental stem cellsOdontogenic genes; dental stem cells
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