Risk for non-AIDS-defining and AIDS-defining cancer of early versus delayed initiation of antiretroviral therapy

2021

BACKGROUND: Immediate initiation of antiretroviral therapy (ART) regardless of CD4 cell count reduces risk for AIDS and non-AIDS-related events in asymptomatic, HIV-positive persons and is the standard of care. However, most HIV-positive persons initiate ART when their CD4 count decreases below 500 × 10 9 cells/L. Consequences of delayed ART on risk for non-AIDS-defining and AIDS-defining cancer, one of the most common reasons for death in HIV, are unclear. OBJECTIVE: To estimate the long-term risk difference for cancer with the immediate ART strategy.DESIGN: Multinational prospective cohort study.SETTING: The D:A:D (Data collection on Adverse events of anti-HIV Drugs) study, which included…

Correlations between isospin dynamics and Intermediate Mass Fragments emission time scales: a probe for the symmetry energy in asymmetric nuclear mat…

2012

We show new data from the $^{64}$Ni+$^{124}$Sn and $^{58}$Ni+$^{112}$Sn reactions studied in direct kinematics with the CHIMERA detector at INFN-LNS and compared with the reverse kinematics reactions at the same incident beam energy (35 A MeV). Analyzing the data with the method of relative velocity correlations, fragments coming from statistical decay of an excited projectile-like (PLF) or target-like (TLF) fragments are discriminated from the ones coming from dynamical emission in the early stages of the reaction. By comparing data of the reverse kinematics experiment with a stochastic mean field (SMF) + GEMINI calculations our results show that observables from neck fragmentation mechani…

Kinematical coincidence method in transfer reactions

2013

A new method to extract high resolution angular distributions from kinematical coincidence measurements in binary reactions is presented. Kinematic is used to extract the center of mass angular distribution from the measured energy spectrum of light particles. Results obtained in the case of 10Be+p-->9Be+d reaction measured with the CHIMERA detector are shown. An angular resolution of few degrees in the center of mass is obtained.

Elastic scattering studies of 16C at 50 MeV/A on proton and deuteron targets with the CHIMERA multidetector at INFN-LNS

2012

At the Laboratori Nazionali del Sud (LNS) in Catania (Italy), light radioactive ion beams have been produced through the In Flight Fragmentation method, using 18O and 13C at 55 MeV/A as primary beams impinging on a 9Be production target. Elastic scattering angular distributions of 16C+p and 16C+d at 50 MeV/A, 10Be+p at 56 MeV/A and 13B+d at 52 MeV/A systems were measured by using the CHIMERA (Charge Heavy Ion Mass and Energy Resolving Array) multidetector and kinematical coincidence technique. The experimental data are fitted by using the optical model. © Published under licence by IOP Publishing Ltd.

Dalla frammentazione del neck alla fissione dinamica: gli esperimenti TimeScale e InKiIsSy al LNS

2013