0000000000700907

AUTHOR

Dimitar Dimitrov

showing 2 related works from this author

The era of reference genomes in conservation genomics

2022

Progress in genome sequencing now enables the large-scale generation of reference genomes. Various international initiatives aim to generate reference genomes representing global biodiversity. These genomes provide unique insights into genomic diversity and architecture, thereby enabling comprehensive analyses of population and functional genomics, and are expected to revolutionize conservation genomics.

QH301 Biology580 Plants (Botany)Genetics -- ResearchEvolutionsbiologibiodiversity conservation; conservation genetics; ERGA; European Reference Genome AtlasConservation genetics; Biodiversity conservation; European Reference Genome Atlas; ERGAAnimal genome mappingudc:630*1GenomeGEERGA[SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE][SDE.BE.BIOD]Environmental Sciences/Biodiversity and Ecology/domain_sde.be.biodERGA ; Biodiversity [MeSH] ; Genomics [MeSH] ; Ecology Evolution Behavior and Systematics ; conservation genetics ; Genome [MeSH] ; biodiversity conservation ; European Reference Genome Atlas3rd-DASGenomicsBiodiversityreferenčni genomi[SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM][SDE.BE.BEC]Environmental Sciences/Biodiversity and Ecology/domain_sde.be.becChemistry10121 Department of Systematic and Evolutionary BotanygenomikaGE Environmental Sciences:Informàtica::Aplicacions de la informàtica::Bioinformàtica [Àrees temàtiques de la UPC]biodiverzitetaSettore BIO/18 - GENETICAeducationQH426 GeneticsQH301European Reference Genome AtlasVDP::Matematikk og Naturvitenskap: 400::Basale biofag: 470[SDE.BE.EVO]Environmental Sciences/Biodiversity and Ecology/domain_sde.be.evoGeneticsconservation genetics ; biodiversity conservation ; European Reference Genome Atlas ; ERGAgenomi10211 Zurich-Basel Plant Science CenterGenomesGenetikBiologyQH426Ecology Evolution Behavior and SystematicsEvolutionary BiologyBiodiversity conservation; Conservation genetics; European Reference Genome AtlasAmbientaleEcologíaGenética1105 Ecology Evolution Behavior and Systematicsconservation geneticsWildlife conservation570 Life sciences; biologyHuman medicinebiodiversity conservationAnimal genetics[SDE.BE]Environmental Sciences/Biodiversity and EcologyGenètica
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Tracing European Founder Lineages in the Near Eastern mtDNA Pool

2000

Founder analysis is a method for analysis of nonrecombining DNA sequence data, with the aim of identification and dating of migrations into new territory. The method picks out founder sequence types in potential source populations and dates lineage clusters deriving from them in the settlement zone of interest. Here, using mtDNA, we apply the approach to the colonization of Europe, to estimate the proportion of modern lineages whose ancestors arrived during each major phase of settlement. To estimate the Palaeolithic and Neolithic contributions to European mtDNA diversity more accurately than was previously achievable, we have now extended the Near Eastern, European, and northern-Caucasus d…

Time FactorsHaplogroup HLineage (evolution)Extrachromosomal InheritanceBiologyDNA MitochondrialHaplogroupMiddle East03 medical and health sciencesGene FrequencyDemic diffusionGeneticsHumansGenetics(clinical)PhylogenyGenetics (clinical)030304 developmental biologyGenetics0303 health sciences030305 genetics & heredityGenetic VariationGene PoolArticlesHaplogroup L3Emigration and ImmigrationFounder EffectEuropeDatabases as TopicHaplotypesMutagenesisEvolutionary biologyGenealogical DNA testHuman mitochondrial DNA haplogroupFounder effectThe American Journal of Human Genetics
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