0000000000701670

AUTHOR

Lalit Singh

showing 2 related works from this author

Intubation Practices and Adverse Peri-intubation Events in Critically Ill Patients From 29 Countries

2021

Importance: Tracheal intubation is one of the most commonly performed and high-risk interventions in critically ill patients. Limited information is available on adverse peri-intubation events. Objective: To evaluate the incidence and nature of adverse peri-intubation events and to assess current practice of intubation in critically ill patients. Design, Setting, and Participants: The International Observational Study to Understand the Impact and Best Practices of Airway Management in Critically Ill Patients (INTUBE) study was an international, multicenter, prospective cohort study involving consecutive critically ill patients undergoing tracheal intubation in the intensive care units (ICUs…

Malemedicine.medical_specialtyCritical Illnessmedicine.medical_treatmentAged; Critical Illness; Female; Heart Arrest; Humans; Hypotension; Hypoxia; Intensive Care Units; Intubation Intratracheal; Logistic Models; Male; Medical Errors; Middle Aged; Prospective Studies; Respiration Artificial; Respiratory Insufficiency; Vasoconstrictor Agents01 natural sciencesNOtracheal intubation ; adverse peri-intubation events03 medical and health sciences0302 clinical medicineInterquartile rangeIntensive careSettore MED/41 - ANESTESIOLOGIAIntubation IntratrachealHumansVasoconstrictor AgentsMedicineIntubationIntubation Critical CareProspective Studies030212 general & internal medicine0101 mathematics610 Medicine & healthHypoxiaProspective cohort studyAgedMedical Errorsbusiness.industryRespiration010102 general mathematicsTracheal intubationGeneral MedicineMiddle AgedRespiration ArtificialHeart ArrestIntratrachealIntensive Care UnitsIntubation procedureLogistic ModelsRespiratory failureArtificialEmergency medicineFemaleAirway managementHypotensionIntubationRespiratory Insufficiencybusiness
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1

2021

Contains fulltext : 232759.pdf (Publisher’s version ) (Closed access) In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to…

0301 basic medicineProgrammed cell deathSettore BIO/06AutophagosomeAutolysosome[SDV]Life Sciences [q-bio]lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4]Autophagy-Related ProteinsReviewComputational biology[SDV.BC]Life Sciences [q-bio]/Cellular BiologyBiologySettore MED/0403 medical and health sciencesstressChaperone-mediated autophagyddc:570AutophagyLC3AnimalsHumanscancerSettore BIO/10Autophagosome; cancer; flux; LC3; lysosome; macroautophagy; neurodegeneration; phagophore; stress; vacuoleSet (psychology)Molecular Biologyvacuole.phagophore030102 biochemistry & molecular biologyvacuolebusiness.industryInterpretation (philosophy)AutophagyAutophagosomesneurodegenerationCell BiologyfluxMulticellular organismmacroautophagy030104 developmental biologyKnowledge baselysosomeAutophagosome; LC3; cancer; flux; lysosome; macroautophagy; neurodegeneration; phagophore; stress; vacuoleBiological AssayLysosomesbusinessBiomarkers[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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