0000000000703602

AUTHOR

Alejandro Lozano-garcía

showing 4 related works from this author

Drug load and memory during intracarotid amobarbital procedure in epilepsy

2021

Background Anti-seizure medications (ASMs) have been related to poor cognitive function, but their relationship with intracarotid amobarbital procedure (IAP) results remains unclear. Aims of the study To elucidate whether the number and drug load of ASMs are associated with memory scores of the IAP and the neuropsychological assessment. Methods Fifty-nine adult patients with drug-resistant epilepsy (mean age = 36.1, SD = 11.6) underwent bilateral IAP (with drawings and words as memory items) and a neuropsychological assessment to assess the risk of post-surgical memory decline. Total ASM drug load was calculated by summing the daily dose/defined daily dose ratio of every ASM of each patient…

Adultmedicine.medical_specialtyAmobarbitalFunctional Laterality03 medical and health sciencesEpilepsy0302 clinical medicineMemoryInternal medicinemedicineHumans030212 general & internal medicineNeuropsychological assessmentEpilepsymedicine.diagnostic_testbusiness.industryConfoundingNeuropsychologyCognitionGeneral MedicineMiddle Agedmedicine.diseaseDefined daily doseEpilepsy Temporal LobeInjections Intra-ArterialPharmaceutical PreparationsNeurologyCardiologyAmobarbitalWada testNeurology (clinical)business030217 neurology & neurosurgerymedicine.drugActa Neurologica Scandinavica
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Respuesta cardiovascular al estrés en pacientes con epilepsia farmacorresistente: datos preliminares

2021

El estrés es un factor de riesgo para las enfermedades cardiovasculares en la población general. La epilepsia se ha considerado un modelo adecuado de estrés crónico, con mayor incidencia de mortalidad cardiovascular que la población general. Este estudio proporciona datos preliminares sobre la respuesta cardiovascular ante un estresor cognitivo y una evaluación neuropsicológica en pacientes con epilepsia, explorando las relaciones entre la respuesta cardiovascular y el rendimiento cognitivo dependiendo del hemisferio responsable de la epilepsia. Treinta y cinco pacientes con epilepsia farmacorresistente, 17 con el área epileptógena(AE) en el hemisferio izquierdo (LH) y 18 con AE en el hemis…

education.field_of_studymedicine.medical_specialtymedicine.diagnostic_testbusiness.industryStressorPopulationDrug Resistant Epilepsymedicine.diseaseEpilepsyInternal medicineCardiologyMedicineChronic stressNeuropsychological assessmentEffects of sleep deprivation on cognitive performanceRisk factorbusinesseducationGeneral PsychologyAnales de Psicología
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The number of anti-seizure medications mediates the relationship between cognitive performance and quality of life in temporal lobe epilepsy

2021

Abstract Objectives To assess whether cognitive performance predicts quality of life (QOL) in patients with drug-resistant temporal lobe epilepsy (TLE), using the Epitrack cognitive screening tool, while considering the mediating role of the number of anti-seizure medications (ASMs) and controlling for seizure-related, social, and emotional factors. Methods Seventy-five adult patients with drug-resistant TLE (mean age = 39.76 years, SD = 11.66) underwent a presurgical neuropsychological assessment. Main Outcome Measures: Cognitive performance (Epitrack), depression (BDI-II), trait anxiety (STAI); and QOL (QOLIE-31) were assessed. Results Adjusting for seizure-related, social, and emotional …

Adultmedia_common.quotation_subjectPopulationAnxietyNeuropsychological Tests03 medical and health sciencesBehavioral NeuroscienceEpilepsyCognition0302 clinical medicineQuality of lifemedicineHumans030212 general & internal medicineEffects of sleep deprivation on cognitive performanceNeuropsychological assessmentCognitive skilleducationmedia_commoneducation.field_of_studymedicine.diagnostic_testbusiness.industryCognitionmedicine.diseasehumanitiesEpilepsy Temporal LobeNeurologyQuality of LifeNeurology (clinical)Worrybusiness030217 neurology & neurosurgeryClinical psychologyEpilepsy & Behavior
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Respuesta cardiovascular al estrés en pacientes con epilepsia farmacorresistente: datos preliminares

2021

El estrés es un factor de riesgo para las enfermedades cardiovasculares en la población general. La epilepsia se ha considerado un modelo adecuado de estrés crónico, con mayor incidencia de mortalidad cardiovascular que la población general. Este estudio proporciona datos preliminares sobre la respuesta cardiovascular ante un estresor cognitivo y una evaluación neuropsicológica en pacientes con epilepsia, explorando las relaciones entre la respuesta cardiovascular y el rendimiento cognitivo dependiendo del hemisferio responsable de la epilepsia. Treinta y cinco pacientes con epilepsia farmacorresistente, 17 con el área epileptógena(AE) en el hemisferio izquierdo (LH) y 18 con AE en el hemis…

Variabilidad cardíaca:1 - Filosofía y psicología::159.9 - Psicología [CDU]Heart rateDrug-resistant epilepsyEstrés agudoFrecuencia cardíacaAcute stressRespuesta cardiovascularHeart rate variabilityEpilepsia farmacorresistenteCardiovascular response
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