0000000000704415

AUTHOR

Antonio Vázquez-prado

One-year follow-up of clinical, metabolic and oxidative stress profile of morbid obese patients after laparoscopic sleeve gastrectomy. 8-oxo-dG as a clinical marker

Obesity has grown worldwide over the last few decades. In its different degrees, obesity is accompanied by many clinical and biochemical alterations reflecting the pathological condition of various body tissues. Among the mechanisms underlying the pathogenesis of obesity and associated complications, oxidative stress (OS) may be playing an important role. In the present study, we have characterized at systemic level the degree of OS status in a group of morbid obese patients (BMI>40 kg/m2) at basal sate and its modulation during one year after bariatric surgery using the laparoscopic sleeve gastrectomy (LSG) technique. As compared with normal weight subjects matched in age, peripheral blood…

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Influencia de la octreótida en la anastomosis tras obstrucción cólica experimental

Resumen Introduccion Se valora el efecto de la octreotida sobre la oclusion experimental del colon y posterior anastomosis. Material y metodo Se realiza una oclusion de colon en dos grupos de ratas Wistar, a uno de los cuales se le administra octreotida. A las 48 h se relaparotomizo a los animales, se valoraron el grado de oclusion y el contenido intestinal y se reseco un fragmento intestinal para estudio histologico, confeccionando una anastomosis termino-terminal. A los 7 dias se reintervino a los animales y se valoraron las complicaciones, determinando la presion de rotura de la anastomosis, la cantidad de colageno que contiene y su histologia. Resultados El grupo tratado con octreotida …

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