0000000000704735

AUTHOR

Lara Nonell

showing 2 related works from this author

Cancer Signaling Transcriptome Is Upregulated in Type 2 Diabetes Mellitus

2020

We aimed to explore the differences in the whole transcriptome of peripheral blood mononuclear cells between elderly individuals with and without type 2 diabetes (T2D). We conducted a microarray-based transcriptome analysis of 19 individuals with T2D and 15 without. Differentially expressed genes according to linear models were submitted to the Ingenuity Pathway Analysis system to conduct a functional enrichment analysis. We established that diseases, biological functions, and canonical signaling pathways were significantly associated with T2D patients when their logarithms of Benjamini&ndash

endocrine system diseasesMicroarrayIntegrinT cellslcsh:Medicine030209 endocrinology & metabolismInflammationPeripheral blood mononuclear cellArticleDiabetis no-insulinodependentTranscriptome03 medical and health scienceschemistry.chemical_compound0302 clinical medicineDownregulation and upregulationmedicinecancerNon-insulin-dependent diabetesCàncer030304 developmental biologyCancer0303 health sciencesbiologybusiness.industrylcsh:Rnutritional and metabolic diseasesGeneral Medicinesignaling pathwayschemistryCèl·lules TGuanosine diphosphateCancer researchbiology.proteintype 2 diabetesmedicine.symptomSignal transductionbusinesstranscriptomemicroarray
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Transcriptional response to a Mediterranean diet intervention exerts a modulatory effect on neuroinflammation signaling pathway.

2020

Background: The Traditional Mediterranean Diet (TMD) is known to have beneficial effects on several chronic diseases. However, data concerning the whole transcriptome modulation of the TMD are scar...

0301 basic medicineMicroarrayMediterranean dietMedicine (miscellaneous)BiologyBioinformaticsDiet MediterraneanTranscriptome03 medical and health sciences0302 clinical medicineRisk FactorsIntervention (counseling)HumansNutsPlant OilsBeneficial effectsOlive OilNeuroinflammation030109 nutrition & dieteticsNutrition and DieteticsGeneral NeuroscienceGeneral Medicinestomatognathic diseasesCardiovascular DiseasesNeuroinflammatory DiseasesLeukocytes MononuclearTranscriptional responseSignal transductionhuman activities030217 neurology & neurosurgerySignal TransductionNutritional neuroscience
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