Trans-cranial Magnetic Resonance-guided Focused UltraSound (tcMRgFUS) system integrated with a 1.5T: an SNR study on DQA phantoms

Background: In recent years transcranial Magnetic Resonance-guided Focused Ultrasound Surgery (tcMRgFUS) treatments have been performed only using 3T units. Since following some internal analysis, planning images obtained using a 1.5T MRI’s body RF coil (as usually done with 3T systems) showed generally reasonable quality in terms of anatomy visualization and SNR but thermal images noise was above acceptable standard for treatments, a dedicated 2-channels head coil was developed (InSightec Ltd.) to ensure an adequate signal-to-noise ratio (SNR). Hence, we present the imaging protocol and the technological methods successfully used with the world-first installation of a certified tcMRgFUS sy…

Hepatocellular carcinoma (HCC) with indeterminate findings at initial CT or MRI: Does imaging follow-up allow detection of conclusive imaging findings before significant tumor growth?

Magnetic Resonance guided Focused Ultrasound Surgery (MRgFUS) for uterine fibroids: our experience on patients’ eligibility

Learning objectives Background Findings and procedure details Conclusion Personal information References

Chirurgia trans-cranica mediante ultrasuoni focalizzati ad alta intensità su guida rm: esperienza preliminare a 1,5T (primi 2 casi trattati)

Scopo del Lavoro Presentiamo i risultati preliminari ottenuti con la prima istallazione italiana di un’apparecchiatura per la neurochirurgia funzionale mediante ultrasuoni focalizzati ad alta intensità su guida RM (trans-cranial MRI-guided Focused Ultrasound Surgery, tcMRgFUS); si tratta tra l’altro della prima apparecchiatura tcMRgFUS al mondo mai installata su uno scanner RM da 1,5T. Tale apparecchiatura è attualmente certificata (CE ed FDA) per trattamenti di neurochirurgia funzionale in pazienti con tremore essenziale (Essential Tremor, ET), Parkinson idiopatico (Parkinson Disease, PD) unilaterale prevalentemente tremorigeno e dolore neuropatico (Neuropathic Pain, NP). Materiali e Metod…

CHIRURGIA NON INVASIVA AD ULTRASUONI FOCALIZZATI RM GUIDATI (MRGFUS) PER IL TRATTAMENTO DEI FIBROMI UTERINI SINTOMATICI: NOSTRA ESPERIENZA SULL'ELEGGIBILITÀ DELLE PAZIENTI

POST-THALAMOTOMY NEUROFUNCTIONAL FINDINGS ON PATIENTS TREATED WITH TRANS-CRANIAL MAGNETIC RESONANCE GUIDED FOCUSED ULTRASOUND SURGERY (TCMRGFUS): PRELIMINARY RESULTS

BACKGROUND AND PURPOSE: We present functional connectivity (FC) changes found in the very first patients treated with the first Italian installation of a trans-cranial MRI-guided Focused Ultrasound Surgery (tcMRgFUS) certified system for functional neurosurgery. TcMRgFUS is a promising new technique for non-invasive treatment of neurologic disorders such as Essential Tremor, tremor associated to Parkinson's Disease and Neuropathic Pain. TcMRgFUS is able to focally target and destroy specific regions in the brain through intact skull, by using a high intensity focused ultrasound beam. Resting state functional Magnetic Resonance Imaging (RS-fMRI) analyses focuses on spontaneous low frequency …