0000000000713441
AUTHOR
A. Bova
Is losartan able to improve renal haemodynamics in hypertensives? a long term study
Exercise performance in hypertensives: felodipine vs cilazapril cross-over study
Analysis of 24-h noninvasive ambulatory blood pressure profiles by a third-degree polynomial approach
Extensive experience of the circadian variation of blood pressure (BP) has been reported. But some problems exist concerning the correct and satisfactory evaluation of 24-h BP profiles. A well-known approach is the Halberg's 'cosinor' method. But it could be considered inadequate for blood pressure recordings because it is based on a rigid model that does not practically fit empirical data. We suggest an approach based on a cubic function as a suitable method for such an analysis. Our investigation studied the behavior of 24-h blood pressure by a model where the function f(t) is a third-degree polynomial. We recruited 52 untreated patients affected by essential hypertension. Ambulatory BP r…