0000000000713460

AUTHOR

P. Pfeiffer

showing 11 related works from this author

Bestimmung von Tri-n-butylphosphat in Plasmapräparaten nach Festphasenextraktion und Kapillar-Gaschromatographie

1988

A simple method for the quantitative determination of tri-n-butylphosphate in blood plasma preparations is described. The sample is passed through an octadecyl extraction column from which tri-n-butylphosphate is eluted with chloroform. By capillary GC 50 micrograms/l tri-n-butylphosphate can be detected with a recovery of more than 90%.

chemistry.chemical_compoundChromatographyChloroformchemistryElutionBiochemistry (medical)Clinical BiochemistryBlood plasmaExtraction (chemistry)educationGeneral MedicineQuantitative determination
researchProduct

Direct true lumen cannulation in type A acute aortic dissection: A review of an 11 years’ experience

2020

ObjectivesDirect true lumen cannulation (DTLC) of the aorta is an alternative cardiopulmonary bypass cannulation technique in the context of type A acute aortic dissection (A-AAD). DTLC has been reported to be effective in restoring adequate perfusion to jeopardized organs. This study reports and compares operative outcomes with DTLC or alternative cannulation techniques in a large cohort of patients with A-AAD.MethodsAll patients who underwent surgery for A-AAD between January 2006 and January 2017 in Mainz university hospital were reviewed. The choice of cannulation technique was left to the operating surgeon, however DTLC was our preference in patients who were in state of shock or showe…

MaleCardiac CatheterizationResuscitationCritical Care and Emergency MedicineCardiovascular ProceduresComputed Tomography AngiographyHealth Care ProvidersCannulationCardiovascular Medicine030204 cardiovascular system & hematologyCardiac CathetersDiagnostic Radiologylaw.inventionPostoperative Complications0302 clinical medicinelawMedicine and Health SciencesMedical PersonnelHospital MortalityProspective StudiesCardiovascular ImagingAortaAortic dissectionCardiopulmonary BypassMultidisciplinaryRadiology and ImagingQRAngiographyMiddle AgedAortic AneurysmSurvival RateProfessionsTreatment OutcomeMedicineFemaleTamponadeAnatomyResearch Articlemedicine.medical_specialtyDeath RatesImaging TechniquesScienceResuscitationCardiologyLumen (anatomy)Surgical and Invasive Medical ProceduresResearch and Analysis Methods03 medical and health sciencesAneurysmPopulation MetricsDiagnostic MedicinePhysiciansmedicineCardiopulmonary bypassCannulaHumansSurvival rateAgedRetrospective StudiesSurgeonsPopulation Biologybusiness.industryBiology and Life SciencesRetrospective cohort studymedicine.diseaseSurgeryHealth CareAortic Dissection030228 respiratory systemPeople and PlacesCardiovascular AnatomyBlood VesselsPopulation GroupingsbusinessPLOS ONE
researchProduct

Short-course radiotherapy followed by chemotherapy before total mesorectal excision (TME) versus preoperative chemoradiotherapy, TME, and optional ad…

2021

BACKGROUND: Systemic relapses remain a major problem in locally advanced rectal cancer. Using short-course radiotherapy followed by chemotherapy and delayed surgery, the Rectal cancer And Preoperative Induction therapy followed by Dedicated Operation (RAPIDO) trial aimed to reduce distant metastases without compromising locoregional control. METHODS: In this multicentre, open-label, randomised, controlled, phase 3 trial, participants were recruited from 54 centres in the Netherlands, Sweden, Spain, Slovenia, Denmark, Norway, and the USA. Patients were eligible if they were aged 18 years or older, with an Eastern Cooperative Oncology Group (ECOG) performance status of 0-1, had a biopsy-prove…

0301 basic medicinemedicine.medical_specialtyPopulationlaw.inventionTumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14]03 medical and health sciencesFolinic acidAll institutes and research themes of the Radboud University Medical Center0302 clinical medicineRandomized controlled triallawTumours of the digestive tract Radboud Institute for Molecular Life Sciences [Radboudumc 14]medicineClinical endpointeducationeducation.field_of_studyPerformance statusbusiness.industryTotal mesorectal excisionOxaliplatinSurgery030104 developmental biologyOncology030220 oncology & carcinogenesisbusinessChemoradiotherapymedicine.drugThe Lancet Oncology
researchProduct

The double stranded RNA associated with the 447 cytoplasmic male sterelity in Vicia faba is packages together with its replicase in cytoplasmic membr…

1990

33 ref.; International audience

VESICULE CYTOPLASMIQUEFEVE[SDV.BBM] Life Sciences [q-bio]/Biochemistry Molecular Biology[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular Biology
researchProduct

Gender Differences in Acute Type A Aortic Dissection

2019

Aortic dissectionmedicine.medical_specialtyAcute typebusiness.industryInternal medicinemedicineCardiologymedicine.diseasebusinessThe Thoracic and Cardiovascular Surgeon
researchProduct

Vers une maitrise du caractère de la stérilité mâle nucleocytoplasmique (SMC) ?

1987

National audience

[SDV] Life Sciences [q-bio][SDE] Environmental Sciences[SDV]Life Sciences [q-bio][SDE]Environmental SciencesComputingMilieux_MISCELLANEOUS
researchProduct

Short- and Long-Term Outcomes after Iatrogenic Type A Aortic Dissection

2019

Aortic dissectionmedicine.medical_specialtybusiness.industryLong term outcomesMedicinebusinessmedicine.diseaseSurgeryThe Thoracic and Cardiovascular Surgeon
researchProduct

Comparison of the killer toxin of several yeasts and the purification of a toxin of type K2

1984

A total of 13 killer toxin producing strains belonging to the genera Saccharomyces, Candida and Pichia were tested against each other and against a sensitive yeast strain. Based on the activity of the toxins 4 different toxins of Saccharomyces cerevisiae, 2 different toxins of Pichia and one toxin of Candida were recognized. The culture filtrate of Pichia and Candida showed a much smaller activity than the strains of Saccharomyces. Extracellular killer toxins of 3 types of Saccharomyces were concentrated and partially purified. The pH optimum and the isoelectric point were determined. The killer toxins of S. cerevisiae strain NCYC 738, strain 399 and strain 28 were glycoproteins and had a m…

Saccharomyces cerevisiae ProteinsSaccharomyces cerevisiaeSaccharomyces cerevisiaemedicine.disease_causeBiochemistryMicrobiologySaccharomycesPichiaMicrobiologySpecies SpecificityYeastsGeneticsExtracellularmedicineIsoelectric PointAmino AcidsMolecular BiologyCandidaPichiachemistry.chemical_classificationbiologyStrain (chemistry)ToxinTemperatureGeneral MedicineHydrogen-Ion ConcentrationMycotoxinsbiology.organism_classificationKiller Factors YeastMolecular WeightIsoelectric pointchemistryBiochemistryGlycoproteinArchives of Microbiology
researchProduct

The Impact of Obesity on the Outcome of Surgical Repair for Acute Type A Aortic Dissection

2019

Surgical repairAortic dissectionmedicine.medical_specialtybusiness.industryAcute typeMedicinebusinessmedicine.diseaseOutcome (game theory)ObesitySurgeryThe Thoracic and Cardiovascular Surgeon
researchProduct

Survival and reinterventions after isolated proximal aortic repair in acute type A aortic dissection.

2018

OBJECTIVES Conventional treatment for acute type A dissection is the replacement of the ascending aorta. This study demonstrates the results of a conventional approach with isolated proximal repair combined with concomitant endovascular procedures. METHODS Replacement of the ascending aorta with or without an open distal anastomosis was defined as isolated proximal repair and was performed in 562/588 patients between January 2004 and June 2017. A total of 68% were DeBakey type I and 32% were DeBakey type II aortic dissections. Concomitant procedures were thoracic endovascular aortic repair (3.6%); visceral, renal and iliac stents (2%); and peripheral bypasses (1.1%). Mean follow-up was 4.6 …

Pulmonary and Respiratory MedicineMaleReoperationmedicine.medical_specialtyAorta Thoracic030204 cardiovascular system & hematologylaw.inventionCoronary artery disease03 medical and health sciences0302 clinical medicinePostoperative ComplicationslawRisk Factorsmedicine.arteryGermanyAscending aortamedicineCardiopulmonary bypassHumansHospital MortalitySurvival rateAgedAortic dissectionAortic Aneurysm Thoracicbusiness.industryMortality rateIncidenceEndovascular ProceduresMiddle Agedmedicine.diseaseSurgerySurvival RateDissectionAortic DissectionTreatment Outcome030228 respiratory systemConcomitantSurgeryFemaleCardiology and Cardiovascular MedicinebusinessInteractive cardiovascular and thoracic surgery
researchProduct

Killer toxins in new isolates of the yeasts Hanseniaspora uvarum and Pichia kluyveri

1985

From various habitats (plant material, fruits, soil), yeasts belonging to the species of Pichia kluyveri and Hanseniaspora uvarum were isolated that showed killer activity. According to the activity spectrum against other yeasts these strains belonged to 11 different groups that were distinguishable from the killer strains K1-K10. The isoelectric points of the killer proteins were in the range of pH 3.5–3.9, the activity optimum was observed at pH 4.2–4.6. Above pH 5 and above a temperature of 25–35°C the killer proteins were inactivated.

ToxinPichia kluyveriBiological activityBiologymedicine.disease_causebiology.organism_classificationHanseniasporaMicrobiologyYeastMicrobiologyIsoelectric pointHanseniaspora uvarumGeneticsmedicineMolecular BiologyPichiaFEMS Microbiology Letters
researchProduct