0000000000714308

AUTHOR

Hanadi Talal Ahmedah

showing 2 related works from this author

Studies to Elucidate the Mechanism of Cardio Protective and Hypotensive Activities of Anogeissus acuminata (Roxb. ex DC.) in Rodents

2020

Anogeissus acuminata (Roxb. ex DC.) is a folkloric medicinal plant in Asia

1Pharmaceutical Scienceacute myocardial infarction 3030204 cardiovascular system & hematologyPharmacologyCreatineAnalytical ChemistryNitric oxidelcsh:QD241-44103 medical and health scienceschemistry.chemical_compound0302 clinical medicinevasorelaxant 4lcsh:Organic chemistryIn vivoDrug DiscoveryRenin–angiotensin systemleft ventricular hypertrophy 2Physical and Theoretical ChemistryCyclic guanosine monophosphate030304 developmental biology0303 health sciencesbiologyOrganic ChemistryAngiotensin-converting enzymehypotensivechemistryChemistry (miscellaneous)biology.proteinMolecular MedicineCreatine kinasehistopathology 6cardio relaxant 5Ex vivoMolecules
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Cucumis sativus l. Seeds ameliorate muscular spasm-induced gastrointestinal and respiratory disorders by simultaneously inhibiting calcium mediated s…

2021

Cucumis sativus L. is globally cultivated as an edible vegetable. Besides its nutritional benefits, it is used in traditional medicines against various ailments. The current study was designed to elucidate the multi-target mechanisms of a C. sativus seeds extract against asthma and diarrhea using network pharmacology along with a molecular docking approach. Furthermore, in-vitro and in-vivo experiments were conducted to verify the mechanistic insight of in silico studies. LC-ESI-MS/MS was performed to identify the bioactive compounds in the extract; later, some compounds were quantified by HPLC. C. sativus seed. EtOH has kaempferol in higher concentration 783.02 µg/g, followed by quercetin …

In silicoPharmaceutical Sciencechemistry.chemical_elementPharmacologyCalciumArticleJejunum<i>Cucumis sativus</i>chemistry.chemical_compoundAntidiarrheal; Asthma; Bronchodilator; Cucumber; Cucumis sativus; HPLC; LC-ESI-MS/MSPharmacy and materia medicaAntidiarrhealDrug Discoverymedicinebiologyasthma; antidiarrheal; bronchodilator; <i>Cucumis sativus</i>; cucumber; HPLC; LC-ESI-MS/MSCucumberRfood and beveragesLC-ESI-MS/MSbiology.organism_classificationAsthmaRS1-441medicine.anatomical_structurechemistryMolecular MedicineMedicineSignal transductionCucumis sativusHPLCKaempferolQuercetinCucumisLuteolinBronchodilator
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