0000000000714928

AUTHOR

Dharaniya Sakthivel

showing 1 related works from this author

Noninvasive Flap Preconditioning by Foam-Mediated External Suction Improves the Survival of Fasciocutaneous Axial-Pattern Flaps in a Type 2 Diabetic …

2018

Background Advances in reconstructive surgery are leading to an increased number of flaps at risk for ischemic necrosis, because of either intrinsic (e.g., larger flap size) or extrinsic (e.g., diabetes) factors. Methods to preoperatively improve flap vascularity and limit postoperative ischemia are lacking. Noninvasive suction, using either a macrodeformational silicone cup interface (external volume expansion) or a microdeformational polyurethane foam interface (foam-mediated external volume expansion), has been shown to induce angiogenesis in tissues. The authors investigated whether the preoperative use of external volume expansion/foam-mediated external volume expansion improves flap s…

Suction (medicine)Reconstructive surgerymedicine.medical_specialtyAngiogenesisTissue ExpansionIschemiaMice ObeseMice Inbred StrainsStimulationSuctionVascular Remodeling030230 surgerySurgical FlapsDiabetes Mellitus ExperimentalNecrosis03 medical and health scienceschemistry.chemical_compound0302 clinical medicineVascularitymedicineAnimalsPostoperative PeriodIschemic PreconditioningInflammationbusiness.industryGraft SurvivalHistologymedicine.diseaseSurgeryVascular endothelial growth factorDisease Models AnimalDiabetes Mellitus Type 2chemistry030220 oncology & carcinogenesisFemaleSurgerymedicine.symptombusinessPlastic and Reconstructive Surgery
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