0000000000722716

AUTHOR

Neves-silva R

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Comparative histological and immunohistochemical study of ameloblastomas and ameloblastic carcinomas

2017

Background This study aimed to compare the histological and immunohistochemical characteristics of ameloblastomas (AM) and ameloblastic carcinomas (AC). Material and Methods Fifteen cases of AM and 9 AC were submitted to hematoxilin and eosin (H&E) and immunohistochemical analysis with the following antibodies: cytokeratins 5,7,8,14 and 19, Ki-67, p53, p63 and the cellular adhesion molecules CD138 (Syndecan-1), E-cadherin and β-catenin. The mean score of the expression of Ki-67 and p53 labelling index (LIs) were compared between the groups using the t test. A value of p<0.05 was considered to be statistically significant. Results All cases were positive for CKs 5, 14 and 19, but negative fo…

tumorsMalePathologyAntibodies Neoplasmameloblastic carcinomaMalignant transformation0302 clinical medicineAmeloblastomaChildp63biologyki-67Middle Aged:CIENCIAS MÉDICAS [UNESCO]ImmunohistochemistryJaw Neoplasms030220 oncology & carcinogenesisKi-67immunohistochemistryUNESCO::CIENCIAS MÉDICASImmunohistochemistry//purl.org/pe-repo/ocde/ford#3.02.11 [https]Femalesyndecan-1 cd138Adultmedicine.medical_specialtyAdolescentgovernment.form_of_governmentcateninMalignancyAmeloblastoma03 medical and health sciencesYoung AdultDentistry Oral Surgery & MedicineexpressionmedicineHumansgeneGeneral DentistryOral Medicine and PathologyCadherinResearchcytokeratinsodontogenic030206 dentistrymedicine.disease//purl.org/pe-repo/ocde/ford#3.02.14 [https]Ameloblastic carcinomaOtorhinolaryngologyCateningovernmentbiology.proteinSurgeryodontogenic-tumorse-cadherin
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